Non-adherence to antimicrobial stewardship prospective audit and feedback advice: Risk factors and clinical consequences |
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| Authors: | Christopher D. Horton Matthew D.M. Rawlins Laurens Manning Paul R. Ingram |
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| Affiliation: | 1. Medical School, University of Western Australia, 35 Stirling Hwy, Crawley, Western Australia, 6009, Australia;2. Department of Pharmacy, Fiona Stanley Hospital, 11 Robin Warren Drive, Murdoch, Western Australia, 6150, Australia;3. Medical School, University of Western Australia, Harry Perkins Research Institute, Fiona Stanley Hospital, 11 Robin Warren Drive, Murdoch, Western Australia, 6150, Australia;4. Department of Infectious Diseases, Fiona Stanley Hospital, 11 Robin Warren Drive, Murdoch, Western Australia, 6150, Australia;5. Department of Microbiology, PathWest Laboratory Medicine, Fiona Stanley Hospital, 11 Robin Warren Drive, Murdoch, Western Australia, 6150, Australia |
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| Abstract: | Amongst 325 patients receiving restricted antimicrobials whose management was subject to antimicrobial stewardship prospective audit and feedback, adherence to advice was 78%. Non-adherence was associated with diabetic patients, giving more than 1 piece of advice and receipt of piperacillin/tazobactam therapy, and was inversely associated with liver disease. Adherence to advice was associated with a one third reduction in duration of antimicrobial use without adversely impacting other infection-related patient outcomes. |
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| Keywords: | Corresponding author. Department of Infectious Diseases, Fiona Stanley Hospital, 11 Robin Warren Drive, Murdoch, WA, 6150, Australia. Infectious diseases Antimicrobial stewardship Prospective audit and feedback Antimicrobial Adherence |
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