| 鲎试剂方法检测木糖醇注射液中细菌内毒素 |
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| 引用本文： | 王宗春,鲁建武,潘细贵. 鲎试剂方法检测木糖醇注射液中细菌内毒素[J]. 武汉大学学报(医学版), 2005, 26(2): 210-211,227 |
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| 作者姓名： | 王宗春 鲁建武 潘细贵 |
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| 作者单位： | 武汉大学人民医院药学部,武汉,430060;武汉大学人民医院药学部,武汉,430060;武汉大学人民医院药学部,武汉,430060 |
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| 摘 要： | 目的:建立快速的木糖醇注射液中细菌内毒素鲎试剂检查法,替代家兔热原检查法。方法:用不同厂家的鲎试剂对不同批号的木糖醇注射液分别进行干扰试验,考察确立木糖醇注射液细菌内毒素检查法。结果:5%木糖醇注射液不干扰鲎试剂与细菌内毒素的凝集反应,检查结果全部为阴性,结果准确可靠。结论:木糖醇注射液可以用鲎试剂检查法取代家兔热原检查法。
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| 关 键 词： | 木糖醇 细菌内毒素 鲎试剂 |
| 文章编号： | 1671-8852(2005)02-0210-02 |
Bacterial Endotoxin Test of Xylitol Injection by Limulus Test |
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| Wang Zongchun,Lu Jianwu,Pan Xigui. Bacterial Endotoxin Test of Xylitol Injection by Limulus Test[J]. Medical Journal of Wuhan University, 2005, 26(2): 210-211,227 |
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| Authors: | Wang Zongchun Lu Jianwu Pan Xigui |
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| Affiliation: | Wang Zongchun,Lu Jianwu,Pan XiguiDept. of Pharmacy,Renmin Hospital,Wuhan University,Wuhan 430060,China |
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| Abstract: | Objective: To study the bacterial endotoxins test of xylitol injection using limulus lysate agent . Methods: By interfering test, the inhibition/enhancement action of xylitol with limulus lysate agent was studied. Results: There was no interference between the sample and the relative tachypleus amebocyte lysate(TAL). Conclusion: The result of bacterial endotoxins test is the same as that of pyrogen test in healthy mature rabbits. |
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| Keywords: | Xylitol Bacterial Endotoxin Limulus Lysate Agent |
| 本文献已被 CNKI 维普 万方数据 等数据库收录！ |
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