104例角膜肿瘤的病理学分析

目的 分析角膜肿瘤的病理学分类以进一步探讨角膜肿瘤切除的原因.方法 对2001年1月至2007年8月眼病理室存档的104例角膜肿瘤病例进行临床分析及组织病理学分析,并分析临床膊诊断与病理诊断是否相符合.结果 良性肿物共82例,占78.85%,包括角膜皮样瘤61例(58.65%)、角膜上皮细胞增生8例(7.69%)、鳞状上皮乳头状瘤5例(4.81%)、角膜缘色素痣6例(5.77%)及肉芽组织增生2例(1.92%);恶性肿物共22例,占21.15%,包括不典型增生4例(3.85%)、原位癌14例(13.46%)、鳞癌3例(2.88%)及视网膜母细胞瘤眼外转移1例(0.96%).结论 角膜肿瘤切除最常见的原因是角膜皮样瘤,其次是上皮内瘤变.

The and pathological analysis of 104 patients with corneal neoplasm

Objective To analyze the pathological classification and the cause of excision of corneal neoplasm. Methods 104 cases (104 eyes) of excision of corneal neoplasm between January 2001 and August 2007 in Henan Eye Institute were reviewed retrospectively, the clinical data and pathological diagnosis were analyzed. Results 82 (78.85%) eyes of 104 eyes with benign neoplasms were found, including 61 eyes (58.65%)with corneal dermoid , 8 eyes (7.69%)with epithelium cell proliferation, 5 eyes (4.81%)with squamous papilloma, 6 eyes( 5.77% ) with pigmented nevus, 2 eyes( 1.92% ) with proliferation of granulation tissue; 22 (21.15%) eyes of 104 eyes with malignant neoplasms were found, including 4 eyes (3.85%)with atypical hyperplasia, 14 eyes( 13.46%)with carcinoma in situ, 3 eyes with squamous cell carcinoma and 1 eyes (0.96%)with extraocular metastasis of retinoblastoma. Conclusion The main cause of exicision of corneal neoplasm is croneal dermoid, the second cause is intraepithelial neoplasm.