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| 质子磁共振波谱分析对早期脑干损伤的临床价值 | |
| 引用本文： | 陈伟强,杨应明,郑丰任,赵虎,何明利,郑少钦,赖润龙.质子磁共振波谱分析对早期脑干损伤的临床价值[J].中国综合临床,2004,20(9):800-802. |
| 作者姓名： | 陈伟强 杨应明 郑丰任 赵虎 何明利 郑少钦 赖润龙 |
| 作者单位： | 1. 515041,广东省汕头市,汕头大学医学院第一附属医院神经外科 2. 汕头大学医学院法医学教研室 3. 徐州医学院附属连云港医院神经内科 |
| 摘 要： | 目的 探讨质子磁共振波谱 (1HMRS)分析对早期脑干损伤程度及预后评估的临床价值。方法 对 76例原发性脑干损伤患者和 10例健康青年志愿者进行脑干薄层磁共振波谱分析 ,观察两组脑干组织中N 乙酰门冬氨酸 (NAA)、总肌酸 (肌酸 磷酸肌酸 ) (Cr)、胆碱 (Cho)值及NAA/Cr、Cho/Cr值的变化 ,分析这些指标与格拉斯哥预后评分 (GOS)和伤后 90d改良Rankin残障程度的相关性。结果 原发性脑干损伤患者脑干组织早期NAA、Cho、Cr值和NAA/Cr、Cho/Cr值均较正常对照组下降 ;MRS积分与GOS、改良Rankin积分间存在显著相关性。结论 1HMRS分析对早期原发性脑干损伤的程度及预后评估有重要价值 |
| 关 键 词： | 颅脑损伤 影像学检查 |
| 文章编号： | 1008-6315(2004)09-0800-03 |
| 修稿时间： | 2004年3月22日 |
Clinical value of proton magnetic resonance spectroscopy on early brain stem injury |
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| Chen Weiqiang,Yang Yingming,Zheng Fengren,et al..Clinical value of proton magnetic resonance spectroscopy on early brain stem injury[J].Clinical Medicine of China,2004,20(9):800-802. | |
| Authors: | Chen Weiqiang Yang Yingming Zheng Fengren |
| Institution: | Chen Weiqiang,Yang Yingming,Zheng Fengren,et al.Department of Neurosurgery,The First Affiliated Hospital,Shantou University Medical College |
| Abstract: | Objective To investigate the effect of proton magnetic resonance spectroscopy( 1H MRS) in the patients with early brain stem injury and to evaluate the prognosis.Methods 76 patients with primary brain stem injury and 10 volunteers were examined with quantitative 1H MRS; the relationship between MRS valuesincluding N acetylasparate(NAA), choline(Cho)?creatine(Cr) ?NAA/Cr? Cho/Cr ] and Glasgow Outcome Scale (GOS), and modified Rankin cripplehood degrees after 90 days were analyzed.Results NAA?Cho?Cr ?NAA/Cr? Cho/Cr in patients with primary brain stem injury were diminished, as compared with normal control volunteers, and MRS value were significantly correlated with GOS scores and modified Rankin scores.Conclusion 1H MRS may have an important clinical value in judging the outcome of patients with primary brain stem injury. |
| Keywords: | Brain injury Imaging examination |
| 本文献已被 CNKI 维普 万方数据 等数据库收录！ | |