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关节软骨细胞和细胞周基质的压缩特性及其对软骨细胞代谢的影响
引用本文:伏治国,董启榕. 关节软骨细胞和细胞周基质的压缩特性及其对软骨细胞代谢的影响[J]. 医用生物力学, 2008, 23(1): 92-96
作者姓名:伏治国  董启榕
作者单位:苏州大学附属第二医院骨科,苏州215004
摘    要:软骨细胞和细胞周基质(pericellular matrix, PCM)的力学特性对于关节软针的生理功能具有重要的意义。软骨细胞在压缩应力下表现出黏弹性固体材料特性,其压缩特性具有各向异性和多相性。PCM对软骨细胞具有明显的力学保护作用。压缩应力影响软骨细胞的代谢活动。软骨细胞和PCM的力学特性有许多仍未澄清,尚需进一步的研究。

关 键 词:软骨细胞  细胞周基质  生物力学  代谢
文章编号:1004-7220(2008)01-0092-05
收稿时间:2007-05-10
修稿时间:2007-08-27

Compressive Mechanical Properties of Chondrocyte and Pericellular Matrix and Its Influence on the Metabolic Activity of Chondrocyte
FU Zhi-guo and DONG Qi-rong. Compressive Mechanical Properties of Chondrocyte and Pericellular Matrix and Its Influence on the Metabolic Activity of Chondrocyte[J]. Journal of Medical Biomechanics, 2008, 23(1): 92-96
Authors:FU Zhi-guo and DONG Qi-rong
Abstract:The normal mechanical properties of the chondrocytes and the pericellular matrix(PCM)is significant for maintaining the healthy articular cartilage. In the compressive stress environment, the chondrocytes exhibit viscoelastic solid material properties with anisotropic and inhomogeneous compressive mechanical characteristics. The PCM plays a definite mechanical protective role for the chondrocytes. The compressive stress may have an important influence on the metabolic activity of the chondrocytes. In spite of these, the biomechanical properties of the chondrocytes and the PCM are not fully understood, and still need further more study.
Keywords:Chondrocyte  Pericellular matrix  Biomechanics  Metabolism
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