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^18F-FDG PET/CT在甲状腺肿瘤原发灶中的应用及SUVmax界值的探讨
引用本文:朱峥嵘,罗灿华,袁建伟,冯彦林,廖珊.^18F-FDG PET/CT在甲状腺肿瘤原发灶中的应用及SUVmax界值的探讨[J].医疗保健器具,2010,17(9):9-12.
作者姓名:朱峥嵘  罗灿华  袁建伟  冯彦林  廖珊
作者单位:1. 广东省佛山市第一人民医院,血管甲状腺外科,广东,佛山,528000
2. 广东省佛山市第一人民医院,核医学科,广东,佛山,528000
3. 广东省佛山市第一人民医院,统计室,广东,佛山,528000
摘    要:目的评价18F-FDG PET-CT在甲状腺肿瘤原发灶的诊断价值。方法 45例经术前B超检查,共50个病灶怀疑甲状腺恶性肿瘤纳入研究,术前行18F-FDG PET/CT检查评价良恶性,术后病理诊断作为"金标准",对比、评价18F-FDG PET/CT的诊断价值及探讨SUVmax的最佳诊断界值。结果 50个病灶,病理诊断26例为恶性肿瘤,24例为良性肿物。18F-FDG PET/CT诊断的敏感度为88.5%,特异度为79.2%。恶性组SUVmax高于良性组。SUVmax最佳诊断界值为1.810。结论对于B超怀疑的甲状腺恶性肿瘤,18F-FDG PET/CT有很好的诊断价值,寻找合适的SUVmax界值有助于提高诊断准确性。

关 键 词:甲状腺肿瘤  PET/CT  18F-FDG  SUVmax

Preoperative Diagnostic Evaluation and SUVmax Cutoff of the Primary Thyroid Nodules with 18F-FDG PET/CT
ZHU Zhengrong,LUO Canhua,YUAN Jianwei,FENG Yanlin,LIAO Shan.Preoperative Diagnostic Evaluation and SUVmax Cutoff of the Primary Thyroid Nodules with 18F-FDG PET/CT[J].Medicine Healthcare Apparatus,2010,17(9):9-12.
Authors:ZHU Zhengrong  LUO Canhua  YUAN Jianwei  FENG Yanlin  LIAO Shan
Institution:1Department of Thyroid and Vascular Surgery,Foshan First People's Hospital,Foshan 528000,Guangdong Province,China;2Department of Nuclear Medicine,Foshan First People's Hospital,Foshan 528000,Guangdong Province,China;3Department of Statistics,Foshan First People's Hospital,Foshan 528000,Guangdong Province,China)
Abstract:Objective To evaluate the preoperative diagnostic evaluation of 18F-FDG PET/CT in primary thyroid nodules.Methods A total of 45 patients with 50 nodules suspected thyroid malignant lesions by ultrasonography were obtained the preoperative 18F-FDG PET/CT.The 18F-FDG PET/CT diagnosis was compared with the pathology diagnosis to find out the evaluation of the 18F-FDG PET/CT and the ideal SUVmax cutoff.Results 26 of 50 thyroid nodules were malignant and 24 were benign.Sensitivity was 88.5% and specificity was 79.2% for 18F-FDG PET/CT respectively.The SUVmax of the malignant group was higher than taht of the benign group.The ideal SUVmax cutoff was 1.810.Conclusion 18F-FDG PET/CT provides a potentially high diagnostic evaluation in primary thyroid nodules which were suspected malignant by ultrasonography.Establishing the adequate SUVmax cutoff could improve the diagnostic correct rate.
Keywords:PET/CT  18F-FDG  SUVmax
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