1201例患者甲状腺细针穿刺临床病理分析

目的 评价甲状腺细针穿刺的临床应用价值.方法 回顾性分析1201例患者甲状腺细针穿刺的临床资料及其细胞病理诊断结果,临床资料包括甲状腺功能化验、甲状腺自身抗体检测以及甲状腺超声检查等.细胞病理诊断分为4类:未诊断,良性病变,可疑恶性和恶性.结果 1201例甲状腺细针穿刺的患者中,未诊断者114例(9.5%),良性病变者999例(83.2%),可疑恶性者67例(5.6%),诊断恶性者21例(1.7%).良性病变中占首位的是桥本甲状腺炎,共有468例,占良性病变的46.8%.细胞病理诊断桥本甲状腺炎的患者中,单结节占18.3%,甲状腺自身抗体阴性率为10.8%,甲状腺毒症占20.9%.在诊断恶性并行手术的17例患者中,16例手术后组织病理检查均为甲状腺癌.诊断恶性的准确率为94.1%.结论 甲状腺细针穿刺是甲状腺疾病诊断和鉴别诊断的可靠方法 .

Fine-needle aspiration of thyroid:An analysis of 1201 patients with clinical and cytopathological resuits

Objective To determine the role of fine-needle aspiration (FNA) in the diagnosis and management of thyroid diseases.Methods 1201 FNAs were performed between 2005-2009 and related clinical records were retrospectively evaluated.Clinical data included thyroid function tests,immunological studies and ultrasound of the thyroid.Cytopathological diagnosis were classified as unsatisfactory,benign,suspicious for malignancy,and positive for malignancy.Results Of 1201 FNA samples,9.5% were classified as unsatisfactory(or undiagnosed),83.2% were classified as benign,5.6% were classified as suspicious,and 1.7% were classified as malignant.Hashimoto's thyroiditis is in the first place of benign lesions,with a total of 468 cases,accounting for 46.8% of benign lesions.Of Hashimoto's thyroiditis diagnosed by FNA,patients with single nodule accounted for 18.3%,thyroid autoantibodies-negative rate was 10.8%,thyrotoxicosis accounted for 20.9%.Among 17 patients who underwent surgery following FNA diagnosis of malignant,16 cases were pathologically confirmed for thyroid cancer.The accuracy of diagnosis of malignant was 94.1%.Conclusion FNA is a very reliable diagnostic method for the evaluation of thyroid diseases.