Semi-synthetic digoxigenin glycosides |
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Authors: | I F Makarevich |
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Institution: | (1) Kharkov Pharmaceutical Chemistry Scientific-Research Institute, USSR |
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Abstract: | Conclusions Starting with digoxigenin, L-rhamnose, D-glucose, and D-xylose, the monoglycosides digoxigenin-3--L-rhamnopyranoside, 3--D-glycopyranoside, and 3--D-xylopyranoside have been synthesized in approximately 40% yield. The biosides digoxigenin 3,12-di--D-glucopyranoside and 3,12-di--D-xylopyranoside were also obtained in approximately 3% yield. The glycosides obtained possessed high cardiotonic activity.Translated from Khimiko-Farmatsevticheskii Zhurnal, No. 5, pp. 23–27, May, 1969. |
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