鄱阳湖血吸虫病重疫区居民病情调查结果分析

目的：通过对血吸虫病重疫区居民病情的分析，探讨Ｂ超在评估血吸虫病病情中的应用价值。方法：对江西省鄱阳湖区某血吸虫病重疫区村居民进行病原学检查、病史询问及Ｂ超检查，分析不同年龄、性别、职业人群Ｂ超图像异常比例及与血吸虫感染和病史的关系。结果：居民血吸虫粪检阳性率２２．９％，肝实质Ｉ级及以上（血吸虫病肝纤维化）的比例为２２．０％。各项Ｂ超检查指标异常比例男性高于女性，高年龄组高于低年龄组。多因素非条件Ｌｏｇｉｓｔｉｃ回归分析表明，性别为多项Ｂ超检查指标异常的危险因素，而肝实质异常的危险因素有年龄、性别、职业、血吸虫感染与否及治疗次数。结论：Ｂ超可以直接反映居民肝、脾损伤，但由于血吸虫病肝纤维化的产生是个体长期感染的累积，寻找反映早期病变的敏感指标仍是Ｂ超应用于病情评估中有待解决的问题。

THE MORBIDITY INVESTIGATION OF RESIDENTS IN A HIGHLY ENDEMIC VILLAGE OF SCHISTOSOMIASIS IN POYANG LAKE REGION

AIM: To investigate the morbidity of residents in a highly endemic village of schistosomiasis, and to evaluate the usefulness of ultrasound in morbidity study. METHODS: Morbidity induced by Schistosoma japonicum was evaluated and compared in target population by using parasitological examination, ultrasound investigation and medical history questionnaire.RESULTS: The schistosome infection rate was 22.9% in the study population and the prevalence of abnormal ultrasound findings in the liver and spleen was high. The abnormal ultrasound findings correlated with sex significantly,the abnormality of liver parenchyma correlated with age, sex, infection status, occupation and the number of treatment after multiple logistic regression analysis. CONCLUSION: The ultrasound examination could find out the direct pathological changes resulting from schistosome infection.