| 高山红景天总甙抗衰老作用机理的实验研究 |
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| 引用本文： | 许晗,尹伟伟,丁鼎.高山红景天总甙抗衰老作用机理的实验研究[J].浙江中医药大学学报,2011,35(2):248-249,252. |
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| 作者姓名： | 许晗 尹伟伟 丁鼎 |
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| 作者单位： | 正大青春宝药业有限公司,杭州,310023 |
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| 摘 要： | 目的]观察红景天总甙抗衰老作用。方法]红景天总甙按3.0g/kg、1.5g/kg、0.75g/kg灌胃给予老年大鼠30d,测血清丙二醛(MDA)含量,脑组织脂褐质(Lf)含量及血清超氧化物歧化酶(SOD)、谷胱甘肽过氧化物酶(GSH-Px)活性。结果]红景天总甙三剂量组均能明显降低老年大鼠血清MDA含量及脑组织Lf含量,提高血清SOD、GSH-Px活性。结论]红景天总甙可能通过改善自由基代谢发挥抗衰老作用。
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| 关 键 词： | 红景天总甙 抗衰老 脂褐素 过氧化脂质 抗氧化酶 |
Experimental Study on the Function of Mountain Crenulin Saponins Delaying Aging |
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| Xu Han,Yin Weiwei,Ding Ding.Experimental Study on the Function of Mountain Crenulin Saponins Delaying Aging[J].Journal of Zhejiang University of Traditional Chinese Medicine,2011,35(2):248-249,252. |
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| Authors: | Xu Han Yin Weiwei Ding Ding |
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| Institution: | Xu Han,Yin Weiwei,Ding Ding Zhengda Qingchunbao Pharmaceutical Co.Ltd.,Hangzhou(310023) |
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| Abstract: | Objective] To observe the delaying aging of Crenulin Saponins.Method] Perfuse Crenulin Saponins to senile rats at 3.0g/kg,1.5 g/kg,0.75 g/kg for 30d,measure MDA,Lf,SOD and GSH-Px activity.Result] Crenulin Saponins can markedly reduce MDA and Lf content,increase SOD and GSH-Px activity.Conclusion] It may exert delaying aging by improving radical metabolism. |
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| Keywords: | Crenulin Saponins delay aging Lf lipid peroxidation antioxidase |
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