A longitudinal study of platelet behaviour and thromboxane production in whole blood in normal pregnancy and the puerperium期刊界 All Journals 搜尽天下杂志传播学术成果专业期刊搜索期刊信息化学术搜索

A longitudinal study of platelet behaviour and thromboxane production in whole blood in normal pregnancy and the puerperium

Authors:	K. A. LOUDEN Trent Regional Health Authority Research Registrar F. BROUGHTON PIPKIN Reader in Reproductive Physiology S. HEPTINSTALL Senior Lecturer S. C. FOX Laboratory Technician J. R. A. MITCHELL Foundation Professor Head of Department E. M. SYMONDS Foundation Professor Head of Department

Affiliation:	Department of Obstetrics and Gynaecology, University Hospital, Nottingham, NG7 2UH;Department of Medicine, University Hospital, Nottingham, NG7 2UH

Abstract:	Summary. A longitudinal study of platelet behaviour (platelet aggregation and release reaction) in whole blood and of serum thromboxane B₂ production was performed before, during and after normal pregnancy. The response of platelets to arachidonic acid and to adrenaline was significantly increased in the third trimester. Six weeks after delivery, values were still modestly increased but return to non-pregnant values was complete by 12 weeks. Serum thromboxane B₂ production was unchanged throughout pregnancy and the puerperium.

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