Ex-PRESS青光眼引流钉植入对原发性开角型青光眼患者眼压的影响

目的 分析Ex-PRESS青光眼引流钉植入对原发性开角型青光眼患者眼压的影响.方法 选取2014年2月至2015年10月本院收治的70例(98眼)原发性开角型青光眼患者,将所有患者随机分为两组,各35例(49眼).对照组采用传统小梁切除术,观察组则采用Ex-PRESS青光眼引流钉植入术,对比两组手术成功率、手术前后眼压变化及术后并发症发生率.结果 观察组患者手术成功率为83.67％,明显高于对照组的65.31％,差异有统计学意义(P＜0.05);术前两组眼压变化比较差异无统计学意义(P＞0.05),术后1周、1个月、3个月,对照组患者眼压值均高于观察组,差异均有统计学意义(均P＜ 0.05);观察组术后并发症发生率为8.16％,低于对照组的22.45％,差异有统计学意义(P＜0.05).结论 Ex-PRESS青光眼引流钉植入可有效控制原发性开角型青光眼患者的眼压,手术成功率及安全性均较高,并发症少,在临床应用中值得推广.

Effect of implantation of Ex-PRESS glaucoma drainage screw on intraocular pressure in patients with primary open angle glaucoma

Objective To analyze the effect of Ex-PRESS glaucoma drainage screw implantation on intraocular pressure in primary open angle glaucoma patients.Methods 70 patients (98 eyes) with primary open angle glaucoma were randomly divided into a control group and an observation group,35 cases (49 eyes) for each group.The control group received conventional trabeculectomy and the observation group were implantated ExPRESS glaucoma drainage screw.The surgery success rate,the intraocular pressure before and after surgery,and the incidence of postoperative complications were compared between these two groups.Results The surgery success rate was 83.67％ in the observation group and 65.31％ in the control group,with a statistical difference (P＜ 0.05).Before operation,there was no s statistical difference in intraocular pressure between these two groups (P＞ 0.05);1 weeks and 1 and 3 months after operation,the intraocular pressures were higher in the observation group than in the control group,with statistical differences (all P ＜ 0.05).The incidence of complications after operation was 8.16％ in the observation group and 22.45％ in the control group,with a statistical difference (P＜ 0.05).Conclusions The implantation of Ex-PRESS glaucoma drainage screw for patients with primary open angle glaucoma can effectively control the intraocular pressure and has high the success rate and safety and few complications,so it is worth being clinically gengeralized.