桂枝茯苓胶囊联合西药治疗慢性盆腔炎患者疗效分析及对炎症因子的影响

目的 分析桂枝茯苓胶囊联合西药治疗慢性盆腔炎患者疗效及对患者炎症因子的影响.方法 慢性盆腔炎患者70例随机分为研究组与对照组各35例.研究组采用桂枝茯苓胶囊联合西药治疗,对照组仅采用西药治疗.两组患者治疗疗程均为3个月经周期.结果 研究组治疗总有效率(94.29％)高于对照组(68.75％),差异有统计学意义(P＜0.05).研究组患者治疗后血清IL-10(27.62±4.67)μg/L]高于对照组(18.42±3.46)μg/L],CRP(5.42±1.27) mg/L]和TNF-α(1.56±0.34) pg/ml]低于对照组(8.13±1.76) mg/L,(2.65±0.54) pg/ml],差异有统计学意义(P＜0.05).研究组不良反应发生率(5.71％)低于对照组(25.71％),差异有统计学意义(P＜0.05).研究组随访6个月复发率(2.86％)低于对照组(34.29％),差异有统计学意义(P＜0.05).结论 桂枝茯苓胶囊联合西药治疗慢性盆腔炎患者疗效显著,且能够增加血清IL-10含量和降低CRP、TNF-α含量,且未见严重用药不良反应、复发率低.

The effect of Guizhi Fuling Capsule combined with western medicine in the treatment of patients with chronic pelvic inflammatory disease and its effect on inflammatory factors

Objective To study the effect of Guizhi Fuling Capsule combined with western medicine in the treatment of patients with chronic pelvic inflammatory disease and its effect on inflammatory factors.Methods 70 cases of chronic pelvic inflammatory disease were randomly divided into study group and control group,35 cases in each group.Study group was treated with Guizhi Fuling Capsule combined with western medicine,while control group was only treated with western medicine.The two groups were treated for 3 menstrual cycles.Results The total efficiency of the study group (94.29％) was higher than that of the control group (68.75％) (P＜0.05).The level of serum IL-10 in the study group after treatment (27.62±4.67) μtg/L] was higher than that in the control group (18.42±3.46)μg/L],the levels of CRP (5.42±1.27)mg/L] and TNF-α (1.56±0.34)pg/ml] were lower than those in the control group (8.13±1.76)mg/L,(2.65±0.54)pg/ml] (P＜0.05).The incidence of adverse reactions in the study group (5.71％) was lower than that in the control group (25.71％) (P＜0.05).The recurrence rate during 6 months of follow-up in the study group (2.86％) was lower than that in the control group (34.29％)(P＜0.05).Conclusiou Guizhi Fuling Capsule combined with western medicine is effective in treating chronic pelvic inflammatory disease,which can increase the level of serum IL-10 and decrease the levels of CRP and TNF-α,without severe adverse reactions,with low recurrence rate.