益母草注射液联合卡前列素氨丁三醇预防剖宫产产后出血的效果观察

目的 探讨益母革注射液联合卡前列素氨丁三醇预防剖宫产产后出血的效果.方法 选择2014年12月至2016年6月行剖宫产产妇102例作为研究对象,根据随机数字表法随机分为2组,分别为对照组(n=51)和观察组(n=51).对照组宫体内注射卡前列素氨丁三醇注射液,观察组在对照组基础上肌肉注射益母草注射液.结果 观察组术后2h出血量(209.38±34.15) ml]和术后24h出血量(287.52±41.32)ml]少于对照组(378.32±51.24) ml,(464.13±57.82)ml],观察组恶露持续时间(13.46±2.52)h]短于对照组(22.32±3.88)h],宫缩持续时间(3.28±0.76)h]长于对照组(1.54±0.36)h] (P＜0.05).观察组治疗后血浆Fib(3.21±0.67) g/L]和D-二聚体(1.10±0.32)mg/L]低于对照组(4.01±0.79) g/L,(2.54±0.56) mg/L],差异有统计学意义(P＜0.05).观察组产后出血发生率(3.92％)低于对照组(21.57％),差异有统计学意义(P＜ 0.05).结论 益母草注射液联合卡前列素氨丁三醇预防剖宫产产后出血效果显著,且可降低产后出血发生率.

Effect observation of leonurus heterophyllus injection combined with carboprost tromethamine in the prevention of caesarean postpartum hemorrhage

Objective To investigate the effect of leonurus heterophyllus injection combined with carboprost tromethamine in the prevention of caesarean postpartum hemorrhage.Methods 102 puerperae undergoing cesarean section from December 2014 to June 2016 were selected as the research object,and randomly divided into the control group (n=51) and the observation group (n=5 I).The control group received uterine muscle injection of carboprost tromethamine,and the observation group received intramuscular injection of leonurus heterophyllus injection on the basis of the control group.Results The amount of bleeding postpartum 2 and 24 h in the observation group were less than those in the control group (209.38±34.15)ml vs.(378.32±51.24)ml,(287.52±41.32)ml vs.(464.13±57.82)ml],the duration of lochia in the observation group was shorter than that in the control group (13.46±2.52)h vs.(22.32±3.88)h],the duration of uterine contraction in the observation group was longer than that in the control group (3.28±0.76)h vs.(l.54±0.36)h].The levels of plasma Fib and D-dimer in the observation group after treatment were lower than those in the control group (3.2 l±0.67)g/L vs.(4.01±0.79) g/L,(1.10-±:0.32)mg/L vs.(2.54±0.56)mg/L;P＜0.05].The incidence of postpartum hemorrhage in the observation group was lower than that in the control group (3.92％ vs.21.57％,P＜0.05).Conclusion Leonurus heterophyllus injection combined with carboprost tromethamine in the prevention of caesarean postpartum hemorrhage has significant effect,which can reduce the incidence of postpartum hemorrhage.