细胞因子在非酒精性脂肪性肝炎发病机制中的作用

随着非酒精性脂肪性肝病发病率的逐年上升及其对健康的危害,包括3种类型:单纯性脂肪肝、脂肪性肝炎和脂肪性肝硬化已受到越来越多的重视,而非酒精性脂肪性肝炎是由单纯性脂肪肝发展为脂肪性肝硬化的必经阶段,了解其发病机制,探讨具有多种生物学效应的细胞因子在非酒精性脂肪性肝炎中的作用,对于弄清其发病机制的多样性有着深刻的意义。

Pathogenesis of nonalcoholic steatohepatitis: the role of cytokines

As an increase in the prevalence of nonalcoholic fatty liver disease (NAFLD) and its harm to human health,People put more and more stress on the three types of NAFLD. Those are nonalcoholic fatty liver (NAFL), nonalcoholic steatohepatitis (NASH) and nonalcoholic cirrhosis. NASH is a critical link in the chain of NAFLD that spans NAFL to cirrhosis. Consequently , understanding the pathogenesis of NASH and studying the role of cytokines which kinds of biological effects in NASH are significantly important to find out the multiple pathogenesis of NASH.