| 离子通道与缺氧性肺血管收缩 |
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| 引用本文： | 王珏,王虹.离子通道与缺氧性肺血管收缩[J].国际呼吸杂志,2008,28(14):883-885. |
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| 作者姓名： | 王珏 王虹 |
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| 作者单位： | 南京医科大学第一附属医院呼吸科,210029 |
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| 摘 要： | 氧敏感性离子通道广泛表达于肺动脉平滑肌细胞,它们在低氧时决定血管的紧张度,参与缺氧性肺血管收缩的发生.本文就急性和慢性缺氧性肺血管收缩时钾离子和钙离子发挥的作用作一简单综述.
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| 关 键 词： | 缺氧性肺血管收缩 钾通道 钙通道 低氧性肺动脉高压 |
Ion channels and hypoxia pulmonary vasoconstriction |
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| WANG Jue,WANG Hong.Ion channels and hypoxia pulmonary vasoconstriction[J].International Journal of Respiration,2008,28(14):883-885. |
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| Authors: | WANG Jue WANG Hong |
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| Abstract: | Oxygen-sensitive ion channels widely expresses in pulmonary vascular smooth muscle cells,which determine vascular tone in hypoxia and are involved in hypoxia pulmonary vasoconstriction. The paper summarizes that roles of K+ and Ca2+ channels in acute and chronic hypoxia pulmonary vasoconstriction. |
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| Keywords: | Hypoxia pulmonary vasoconstriction K+ channels Ca2+ channels Hypoxia pulmonary hypertension |
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