Phosphatidate phosphatase activity in the blood fluke, Schistosoma mansoni |
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| Authors: | M S Rahman R B Podesta |
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| Affiliation: | Membrane Biology Laboratory, Department of Zoology, University of Western Ontario, London, Canada N6A 5B7 |
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| Abstract: | Phosphatidate phosphatase activity was found in tissue homogenates and a multilamellar body fraction of Schistosoma mansoni. The identity of the enzyme activity was established on the basis of its pH optimum and inhibition by Mg2+, Ca2+ and Tween 20. A seven-fold enrichment of enzyme activity occurred in response to fractionation of the multilamellar bodies. The importance of this enzyme is discussed in terms of its being a marker enzyme and its central role in phospholipid biosynthesis. |
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| Keywords: | Phosphatidate phosphatase Multilamellar body PAPase phosphatidate phosphatase MLB multilamellar bodies |
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