多规则控制方法在实验室室内质控中的应用

目的探讨12．5s／40．6s／8^x-／21．6s和13s／4ls／10^x-／22。两种多规则控制方法的实用性及性能，以提高误差的检出能力。方法应用常用的13。／4I，／10‘／22。多规则控制方法和修改的12．5~／40．6B／8。／21．6。多规则控制方法分别对tiBsAg、HCV抗体、H／V抗体、梅毒螺旋体（TP）抗体四项ELISA试验获得的控制数据进行检验，比较两种多规则控制方法对四项El。ISA试验的误差检出概率。结果12．5／40．6s／8。／2l-6g多规则控制方法对HBsAg、HCV抗体、HIV抗体、TP抗体四项ELISA试验的误差检出概率分别为7．69％、4．54％、8．33％、9．04％；135／4t,／10^x-/22g多规则控制方法的误差检出概率分别为0、0、2．38％、4．22％。结论变异系数小于15％时，12．5s／40瓜／8’／2I幽多规则控制方法的误差检出概率高于13s／4Is／10^x-／22s多规则控制方法，可用于误差较小时需较高的误差检出概率的质控情况；变异系数大于15％时，两种多规则控制方法的误差检出概率差异没有统计学意义。

The application of Westgard multi-rule quality control method in internal quality control

Objective To study the practicability and performance of 12.5s/40.6s/8^x-/21.6, and 13,/41s/I0s/22, multi - rule quality control methods to increase the detection capability of error. Methods By commonly used 13s/41s/l0^x-/22s method and modified 12.5s/40.6s/8^x-/2i.6s multi - rule quality control method to test the data of HBsAg,HCV,HIV and TP in ELISA. Study the difference of error detection between the two multi- rule quality control methods in the four ELISA tests. Results The error_deteetion by 12.ss/go.6s/SX/2t.6s are 7.69% .4.54% ,8. 33% ,9.04% ,and by 13s/41,/10^x-/22g are 0,0,2.38% ,4.22% in the four ELISA tests. Conclusion When the coefficient of variation（CV） less than 15 %, the error detection of the modified method is more than the commonly used method,which can be used in the condition that it needs high error detection in small errors;when the CV more than 15 %, the two methods have not the Statistical significance.