| 雅连和味连对内毒素致小鼠死亡率的影响 |
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| 引用本文： | 赵云龙,冯蓓,周宜,曹世霞. 雅连和味连对内毒素致小鼠死亡率的影响[J]. 辽宁中医杂志, 2011, 0(7): 1448-1449 |
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| 作者姓名： | 赵云龙 冯蓓 周宜 曹世霞 |
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| 作者单位： | 成都中医药大学基础医学院; |
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| 基金项目： | 国家“十一五”科技支撑计划课题(2007BAI40BO6) |
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| 摘 要： | 目的:研究雅连和味连对内毒素所致小鼠死亡率的影响。方法:采用小鼠尾静脉注射脂多糖的方法,连续48h观察小鼠死亡情况。结果:味连小剂量组能明显延长小鼠受脂多糖攻击后的存活时间(P<0.01),雅连小剂量组和味连小剂量组均能降低脂多糖致小鼠死亡率,与模型组相比,差异有统计学意义(P<0.01,P<0.001)。结论:味连小剂量能够明显延长内毒素小鼠的生存时间,降低死亡率,其作用优于雅连。
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| 关 键 词： | 雅连 味连 内毒素 |
The Protective Effects of Coptis Chinensis Franch and C.Deltoidea C.Y. Chenget Hsiao on Endotoxin Challenged Mice |
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| ZHAO Yun-long,FENG Bei,ZHOU Yi,CAO Shi-xia. The Protective Effects of Coptis Chinensis Franch and C.Deltoidea C.Y. Chenget Hsiao on Endotoxin Challenged Mice[J]. Liaoning Journal of Traditional Chinese Medicine, 2011, 0(7): 1448-1449 |
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| Authors: | ZHAO Yun-long FENG Bei ZHOU Yi CAO Shi-xia |
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| Affiliation: | ZHAO Yun-long,FENG Bei,ZHOU Yi,CAO Shi-xia(Institute of Basic Medical Sciences of Chengdu TCM University,Chengdu 611130,Sichuan,China) |
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| Abstract: | Objective:To compare the protective effects of C.deltoidea C.Y.Chenget Hsiao(Ya lian)and Coptis chinensis Franch(Wei lian) On endotoxin(LPS)challenged mice.Methods:To use the method by intravenous injection of endotoxin in mice for 48-hour continuous observation of the death of mice.Results:Coptis chinensis Franch(Wei lian)with low dose can obvious prolong the survival time of mice which attacked by LPS(P<0.01),C.deltoidea C.Y.Chenget Hsiao(Ya lian)with low dose and Coptis chinensis Franch(Wei lian)with low... |
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| Keywords: | Coptis chinensis Franch(Wei lian) C.deltoidea C.Y.Chenget Hsiao(Ya lian) Endotoxin |
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