| 化瘀消脂止痛膏主要药效学研究 |
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| 引用本文： | 李德爱,武刚毅,刘峙,李小纪.化瘀消脂止痛膏主要药效学研究[J].中国医药导报,2011,8(2):53-54. |
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| 作者姓名： | 李德爱 武刚毅 刘峙 李小纪 |
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| 作者单位： | 青岛市市立医院,山东青岛,266011 |
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| 摘 要： | 目的：探讨化瘀消脂止痛膏降血脂及改善血液流变学的作用。方法：以日本大耳白家兔为高脂模型,以总胆固醇（TC）、三酰甘油（TG）、高密度脂蛋白-胆固醇（HDL-C）和低密度脂蛋白-胆固醇（LDL-C）为指标,研究化瘀消脂止痛膏降脂作用;以Wistar大鼠为血瘀证模型,测定血液流变学相关指标,研究化瘀消脂止痛膏对血液流变学的影响。结果：化瘀消脂止痛膏能显著地降低高脂动物的胆固醇和低密度脂蛋白-胆固醇,也可降低血清三酰甘油含量,并能明显降低血瘀证动物的全血黏度、血浆黏度和血纤维蛋白原含量,降低血小板黏附率。结论：化瘀消脂止痛膏能降血脂,改善血液流变学。
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| 关 键 词： | 化瘀消脂止痛膏 药效学 血脂 血液流变学 |
Study on main pharmacodynamic of Huayu Xiaozhi Zhitong Ointment |
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| LI Deai,WU Gangyi,LIU Zhi,LI Xiaoji.Study on main pharmacodynamic of Huayu Xiaozhi Zhitong Ointment[J].China Medical Herald,2011,8(2):53-54. |
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| Authors: | LI Deai WU Gangyi LIU Zhi LI Xiaoji |
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| Institution: | LI De'ai,WU Gangyi*,LIU Zhi,LI Xiaoji(Qingdao Municipal Hospital,Qingdao 266011,China) |
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| Abstract: | Objective: To investigate the effect of Huayu Xiaozhi Zhitong Ointment on decreasing the blood lipid and improving the hemorheology.Methods: The male rabbits were used as the hyperlipidemia models.The total cholesterol(TC),triglyceride(TG),high density lipoprotein cholesterol(HDL-C) and low density lipoprotein cholesterol(LDL-C) were used as the indexes.The effect of Huayu Xiaozhi Zhitong Ointment on decreasing blood lipid was studied;the Wistar rats were used as blood stasis models.The hemorheological inde... |
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| Keywords: | Huayu Xiaozhi Zhitong Ointment Pharmacodynamic Blood lipid Hemorheology |
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