| 骨髓间充质干细胞对脊髓损伤的修复 |
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| 引用本文： | 王海峰. 骨髓间充质干细胞对脊髓损伤的修复[J]. 医学综述, 2011, 17(10): 1470-1472 |
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| 作者姓名： | 王海峰 |
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| 作者单位： | 首都医科大学,北京市神经外科研究所,北京,100050 |
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| 摘 要： | 脊髓间充质干细胞(MSCs)是近年来对脊髓损伤(SCI)修复研究的热点。移植的MSCs能向损伤部位自主移行,并分泌神经营养物质和细胞因子,促进损伤脊髓修复和神经功能恢复,显著改善SCI患者的神经功能缺失。通过查阅近年来国内外相关文献,对MSCs生物学特性、移植治疗SC I的实验研究、治疗机制进行讨论和分析,为SCI及相关研究提供参考资料。
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| 关 键 词： | 骨髓间充质干细胞 脊髓损伤 修复 |
The Restoration of Spinal Cord Injury by Bone Mesenchymal Stem Cells |
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| WANG Hai-feng. The Restoration of Spinal Cord Injury by Bone Mesenchymal Stem Cells[J]. Medical Recapitulate, 2011, 17(10): 1470-1472 |
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| Authors: | WANG Hai-feng |
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| Affiliation: | WANG Hai-feng,AN Yi-hua.(Department of Stem Cell of Capital Medical University,Beijing Neurosurgerical Institute,Beijing 100050,China) |
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| Abstract: | The research on restoration of spinal cord injury(SCI)is focusing on bone mesenchymal stem cells(MSCs)recently.The transplanted MSCs can automatically move to the injury,secrete neurotrophic substance and cytokines,and promote restoration of SCI and neural function,which may significantly improve on SCI patients neurological function missing.Here is to discuss and analyze the MSCs biological nature,experiment of transplant treatment for SCI and the treatment mechanism through reviewing on related papers pub... |
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| Keywords: | Bone mesenchymal stem cells Spinal cord injury Restoration |
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