| 荆门地区长寿老人血浆FFA亚组分及血脂分析 |
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| 引用本文： | 左玲,宁乐平. 荆门地区长寿老人血浆FFA亚组分及血脂分析[J]. 医学综述, 2011, 17(12): 1885-1887,1891 |
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| 作者姓名： | 左玲 宁乐平 |
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| 作者单位： | 1. 湖北省荆门市第一人民医院,湖北,荆门,448000
2. 武汉大学中南医院,武汉,430071 |
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| 摘 要： | 目的分析荆门地区钟祥长寿村老人血浆总胆固醇(TC)、三酰甘油(TG)、低密度脂蛋白胆固醇(LDL-C)、高密度脂蛋白胆固醇(HDL-C)以及游离脂肪酸(FFA)亚组分,并探讨血脂与长寿的相关性。方法研究设长寿组、正常对照组,取受试者空腹静脉血,分离新鲜血浆,用高效液相色谱法检测血浆FFA,用全自动生化分析仪检测血浆血糖(GLU)、TC、TG、LDL-C、HDL-C。结果与正常对照组比较,长寿组中GLU、TC、TG、HDL-C、TFA、不饱和脂肪酸等显著升高(P<0.05),而LDL-C显著降低(P<0.01),但是都在正常参考范围内。FFA亚组分中,除C14∶0和C20∶4没有显著差异外,C18∶2显著降低(P<0.01)外,其余所测FFA亚组分均显著升高(P<0.05)。结论长寿老人血浆FFA亚组分中,以C18∶2浓度降低和C20∶5浓度升高最显著,可能与延缓衰老有关。
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| 关 键 词： | 长寿 血脂 游离脂肪酸 高效液相色谱法 |
Analysis of Plasma FFA Subfraction and Lipid in Long-lived People in Jingmen Area |
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| ZUO Ling,NING Yue-ping. Analysis of Plasma FFA Subfraction and Lipid in Long-lived People in Jingmen Area[J]. Medical Recapitulate, 2011, 17(12): 1885-1887,1891 |
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| Authors: | ZUO Ling NING Yue-ping |
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| Affiliation: | 1.Hubei Jingmen First People′s Hospital,Jingmen 448000,China;2.Zhongnan Hospital of Wuhan University,Wuhan 430071,China) |
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| Abstract: | Objective To analyze the plasma total cholesterol(TC),triglyceride(TG),low-density lipoprotein cholesterol(LDL-C),hihg-density lipoprotein cholesterol(HDL-C) subfractions,and free fatty acids(FFA) and blood lipids in the elderly from the longevity village in Hubei Zhongxiang and discuss the correlation between lipid and longevity.Methods Longevity group and normal control group were set up,fasting venous blood were taken from the subjects,fresh plasma were separated,plasma FFA spectrum was tested by high pe... |
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| Keywords: | Longevity Lipid Free fatty acids High performance liquid chromatography |
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