急性缺血性卒中机械取栓治疗的现状

在出现不可逆性神经细胞损伤之前迅速安全地再通血管、恢复血流以挽救缺血半暗带组织，是急性缺血性卒中（acute ischemic stroke, AIS ）的主要治疗目标。目前，在AIS早期开通血管的方法主要是静脉溶栓，但由于其治疗时间窗短、血管再通率低、出血并发症发生率高等原因，效果常不令人满意。近年来，随着机械取栓装置的研发及介入技术的发展，使得AIS的治疗时间窗显著延长，血管开通率显著提高，临床转归显著改善，机械取栓治疗已显示出良好的应用前景。

Current status of mechanical thrombectomy for acute ischemic stroke

Before irreversible neuronal damage occurs, quickly and securely recanalize vessels and restore blood flow to save the ischemic penumbra tissue are the main therapeutic target for acute ischemic stroke (AIS). Currently, the method for recanalization in early AIS is intravenous thrombolysis, how ever, the effect of intravenous thrombolysis is often not satisfactory because of the reasons, such as its short treatment time w indow , low vascular recanalization rate, and high incidence of bleeding complications. In recent years, w ith the research and development of mechanical thrombectomy device and the development of interventional technology, the therapeutic time w indow of AIS has been significantly prolonged, the vascular recanalization rate has increased significantly, the clinical outcome has improved significantly, and the treatment of mechanical thrombectomy has show n good application prospects.