心房颤动患者卒中预防中的抗凝治疗：安全性和依从性

心房颤动（atrial fibrilation, AF）最主要的危害是卒中和体循环栓塞事件。最新的资料表明，高达1/3的卒中患者的病因可能为AF ，其导致的卒中致残率和致死率均高于其他类型卒中。因此，对AF患者的卒中预防至关重要。抗凝治疗是AF患者卒中预防的核心策略，文章就AF患者抗凝治疗的安全性和依从性研究进展进行了综述。

Anticoagulant therapy in patients w ith atrial fibrillation:safety and compliance

The most important harms of atrial fibrilation are stroke and the embolic events of the systemic circulation. The latest data have show n that the etiology of up to 1/3 of stroke patients w as atrial fibrilation. The stroke morbidity and mortality caused by atrial fibrilation are higher than other types of stroke. So the prevention of stroke is very important for patients with atrial fibrilation. The anticoagulant therapy is the core strategy for stroke prevention in patients with atrial fibrilation. This article reviews the advances in research on the safety and compliance of anticoagulation therapy in patients w ith atrial fibrilation.