傅青主生化汤对再次剖宫产术后子宫复旧的影响

目的 探讨傅青主生化汤加减对再次剖宫产术后子宫复旧的影响.方法 112例再次行剖宫产术的产妇按随机数字表法随机分为2组,各56例.对照组给予缩宫素(10IU,静脉滴注,1次/d),共3d,试验组在对照组基础上服用傅青主生化汤加减,共5d.随访42 d.比较2组产妇术后恶露持续时间、血红蛋白浓度和子宫超声异常.结果 试验组血性恶露持续时间[(5.1±1.2)d比(5.8±1.3)d;t=-2.734,P=0.007]、血性+浆液恶露持续时间[25.0 (21.0～29.8)d比29.0 (26.0～33.8)d;Z=-3.873,P＜0.001]均显著短于对照组;42d时试验组恶露干净率[94.9％比82.1％;x2=4.264,P=0.039]、血红蛋白水平[(115.43±10.68) g/L比(104.29±9.90) g/L;t=5.725,P＜0.001]均显著高于对照组;子宫三径之和显著小于对照组[(14.2±1.0) cm比(14.8±1.3) cm;t=-2.686,P=0.008];试验组宫腔积液发生率低于对照组(3.6％比17.9％;x2=5.973,P=0.015).结论 傅青主生化汤可促进再次剖宫产术后子宫复旧.

Effect of Fu Qingzhu's Shenghua decoction on uterine involution after repeat cesarean section

Objective To observe the effect of modified Fu Qingzhu's Shenghua decoction on uterine involution after repeat cesarean section.Methods Randomized and parallel design was adopted in the study.A total of 112 cases were recruited into an observation group and a control group.56 cases in the observation group were treated with oral Fu Qingzhu's Shenghua decoction for 5 days,while 56 cases in control group were treated without any herbs.The follow-up was 42 days.Duration of lochia,hemoglobin concentration,and abnormalities of uterine ultrasound were observed.Results Duration of lochia rubra (5.1 ± 1.2 d vs.5.8 ± 1.3 d;t=-2.734,P=0.007) and the duration of lochia rubra and lochia serosa in the observation group 25.0 (21.0,29.8) d vs.29.0 (26.0,33.8) d;Z=3.873,P＜0.001) were all lower than the control group.The lochia complete ration in 42 days (94.9％ vs.82.1％,x2=4.264),the average hemoglobin concentration (115.43 ± 10.68 g/L vs.104.29 ± 9.90 g/L,F=4.159) and sum of the three uterine diameters (14.2 ± 1.0 cm vs.14.8 ± 1.3 cm,t=-2.686,P=0.008) in the observation group were all higher than the control group.The incidence of uterine cavity hydrops (3.57％ vs.17.85％,P=0.015) in the observation group was lower than the control group.Conclusion Fu Qingzhu's Shenghua decoction has promotive effects on uterine involution after repeat cesarean section.