国家自然基金重点项目(81230026);江苏省领军人才和创新团队项目(LJ201101)Fund programs State Key Program of National Natural Science Foundation of China(81230026),Leading Talent and Innovation Team Project of Jiangsu Province(LJ201101)
Moyamoya disease is a progressive cerebrovascular occlusive disease, which is characterized by the formation of abnormal vascular network at the brain base. It is an important cause of stroke in children and adults. Now, the etiology of moyamoya disease is not clear. This article reviews its pathogenesis from 3 aspects, including genetic factors, angiogenesis, and immune inflammation.