细胞因子在心脏移植排斥反应中的作用研究进展 |
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引用本文: | 周翔辉,马维江,徐忠能. 细胞因子在心脏移植排斥反应中的作用研究进展[J]. 国际免疫学杂志, 2016, 0(2): 189-192. DOI: 10.3760/cma.j.issn.1673-4394.2016.02.020 |
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作者姓名: | 周翔辉 马维江 徐忠能 |
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作者单位: | 1. 650000,昆明市第一人民医院/昆明医科大学附属甘美医院心胸外科;2. 650500,昆明医科大学第二临床医学院 |
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摘 要: | 器官移植技术的发展突飞猛进,但宿主移植排斥反应是限制器官移植的一大障碍,其本质上是一种针对异型移植抗原的特异性免疫应答,已成为目前研究的热点.移植排斥反应过程机理复杂,涉及众多细胞因子的参与,白细胞介素(IL)-2、IL-4、干扰素(INF)-γ、IL-10等均在其过程中发挥重要作用.了解细胞因子与移植排斥反应的关系很有意义.
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关 键 词: | 移植 免疫排斥 免疫耐受 细胞因子 |
Research progress of the role of cytokines in heart transplant rejection |
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Abstract: | Organ transplantation is developed by leaps and bounds,however,there is a big barrier that the main graft rejection reaction which limits organ transplantation.It is a kind of specific immune response to different transplantation antigens substantially.The mechanism and process of graft rejection reaction is complicated,many cytokines(IL-2、IL-4 、INF-γ、IL-10) play a vital role on organ transplant rejection.It is important to summarize the relationship between graft rejection reaction and cytokines. |
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Keywords: | Transplant Immune rejection Immune tolerance Cytokines |
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