低能量激光对2型糖尿病合并慢性牙周炎患者血糖代谢指标及超敏C反应蛋白的影响 |
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引用本文: | 李萌萌,赵燕娟,祝书金,李荣华. 低能量激光对2型糖尿病合并慢性牙周炎患者血糖代谢指标及超敏C反应蛋白的影响[J]. 国际生物医学工程杂志, 2016, 0(1): 24-27. DOI: 10.3760/cma.j.issn.1673-4181.2016.01.006 |
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作者姓名: | 李萌萌 赵燕娟 祝书金 李荣华 |
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作者单位: | 1. 300192,天津市第一中心医院口腔科;2. 天津市中医药大学第一附属医院口腔科 |
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基金项目: | 天津市卫生局科技基金资助项目(2013KZ032),Science and Technology Fund of Health Bureau of Tianjin(2013KZ032) |
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摘 要: | 目的 观察低能量激光疗法(LLLT)对2型糖尿病合并慢性牙周炎(DMCP)患者牙周临床指标、血清超敏C反应蛋白(hs-CRP)和血糖代谢指标的影响,探讨低能量激光的干预疗效.方法 选择90例DMCP患者,随机分为A组(基础治疗)、B组(基础治疗+LLLT)及C组(对照组)3组,于治疗前、治疗后3个月时分别检测3组患者牙周指数(牙周探诊深度(PD)、临床附着丧失(CAL)、龈沟出血指数(SBI))、hs-CRP、糖化血红蛋白(HbA1c)及空腹血糖(FPG)水平,并分析、比较其变化.结果 治疗后A、B两组的PD、CAL、SBI及hs-CRP均有所改善,其差异有统计学意义(P<0.05),其中B组效果更为显著(P<0.01);A、B两组HbA1c、FPG水平呈下降趋势,其中B组差异有统计学意义(P<0.05).结论 LLLT对于DMCP患者可显著控制其牙周炎症、降低血清hs-CRP水平及改善血糖水平,并预防糖尿病并发症的发生.
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关 键 词: | 牙周炎 低能量激光疗法 2型糖尿病 超敏C反应蛋白 |
Effect of low 1evel laser treatment on metabolic control and high-sensitivity C-reactive protein of type 2 diabetes mellitus combined chronic peridontitis patients |
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Abstract: | Objective To investigate the effect of low 1evel laser treatment (LLLT) on periodontal clinical index,high-sensitivity C-reactive protein (hs-CRP) and metabolic control in patients of type 2 diabetes mellitus combined chronic peridontitis.Methods Nighty patients with type 2 diabetes combined chronic peridontitis were divided into three groups:initial periodontal therapy (group A),initial therapy combined with LLLT (group B) and control group (group C).The periodontal clinical parameters including periodontal probing depth (PD),clinical attachment loss (CAL),sulcus bleeding index (SBI),hs-CRP,HbA1c and fasting blood glucose (FBG) were tested before and at three months after therapy.Results The periodontal clinical parameters (PD,CAL,SBI) and hsCRP in group A and B improved significantly compared with that of group C after therapy (P<0.05),with group B had more significant difference (P<0.01).For the levels of HbA1c and FPG,group A and B showed downtrend,and more obvious outcome was detected in group B (P<0.05).Conclusions LLLT can effectively improve periodontal status,hs-CRP levels and metabolic control of patients with type 2 diabetes combined with chronic peridontitis,and thus to prevent the occurrence of diabetes complications. |
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Keywords: | Periodontitis Low 1evellaser treatment Type 2 diabetes High-sensitivity C-reactive protein |
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