| 烟雾病与免疫炎症 |
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| 引用本文： | 陈祥,徐运. 烟雾病与免疫炎症[J]. 国际脑血管病杂志, 2016, 0(2): 146-149. DOI: 10.3760/cma.j.issn.1673-4165.2016.02.012 |
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| 作者姓名： | 陈祥 徐运 |
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| 作者单位： | 1. 210008 南京大学医学院附属鼓楼医院神经内科; 510080 广州，中山大学附属第一医院神经内科;2. 210008,南京大学医学院附属鼓楼医院神经内科 |
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| 基金项目： | 国家自然基金重点项目(81230026)；江苏省领军人才和创新团队项目(LJ201101)Fund programs State Key Program of National Natural Science Foundation of China(81230026)，Leading Talent and Innovation Team Project of Jiangsu Province(LJ201101) |
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| 摘 要： | 烟雾病是一种慢性进展性脑血管病，主要表现为双侧颈内动脉进行性闭塞并伴有脑底代偿增生的异常血管网形成。烟雾病的病理学机制尚不清楚。越来越多的证据表明免疫炎症可能在其发生和发展过程中发挥着重要作用。烟雾病患者可见多种炎性因子和免疫蛋白表达异常。文章就近年来有关免疫炎症在烟雾病中的可能作用机制进行了综述。
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| 关 键 词： | 烟雾病 自身免疫疾病 炎症 |
Moyamoya disease and immune inflammation |
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| Abstract: | Moyamoya disease is a chronic progressive cerebrovascular disease. Its main manifestation is bilateral internal carotid artery progressive stenosis w ith abnormal vascular netw ork formation of the compensatory hyperplasia in brain base. The pathological mechanism of moyamoya disease is not clear. Grow ing evidence has suggested that immune inflammation may play an important role in its occurrence and development process. Abnormal expression of various inflammatory cytokines and immune proteins can be observed in patients w ith moyamoya disease. This article review s the possible mechanism of immune inflammation in moyamoya disease in recent years. |
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| Keywords: | Moyamoya Disease Autoimmune Diseases Inflammation |
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