新疆地区维族与汉族脑梗死急性期患者血尿酸水平对照研究

目的:对比观察新疆地区维吾尔族与汉族脑梗死急性期患者的血尿酸(UA)水平。方法:选取脑梗死急性期汉族患者323例(汉族组)与维吾尔族患者144例(维族组),检测血清UA水平,了解TOAST分型与血UA的关系。结果:汉族组和维族组的UA水平分别为(316.17±89.65)、(340.41±87.83)μmol/L,后者高于前者,有显著性差异(t=-2.715,P0.01)。2组吸烟、饮酒各所占的比例,有显著性差异(P0.01)。2组TOAST分型各亚型构成比比较,差异无统计学意义(χ2=0.824,P0.05);2组LAA型血UA水平比较,差异有统计学意义(P0.05);SAO型、CE型血UA水平比较,差异无统计学意义(P0.05)。结论:维族与汉族脑梗死急性期患者不同TOAST分型血尿酸水平升高也不同。

A Parallel Study of Serum Uric Acid in both Xinjiang Uygur and Han Nationality with Acute Cerebral Infarction

Objective: To explore some risk factors between Xinjiang Uygur and Han Nationality patients with a-cute cerebral infarction based on TOAST classification. Methods: Patients diagnosed with acute cerebral infarc-tion were enrolled, including 144 cases of Uygur Nationality patients and 323 cases of Han Nationality. The serum uric acid (UA) level was detected in all the patients. Results: The serum UA levels were (316.17±89.65) μmol/L in Han patients group and (340.41±87.83) μmol/L in Uygur patients group respectively (P<0.01). The percentage of smoking, drinking alcohol and combining coronary heart disease were significantly different between the two groups(P<0.01). There was no significant difference in subtype constituent ratios in TOAST classification between the two groups(χ2=0.467, P>0.05). For the LAA subtype patients, the levels of blood UV was significantly different between the two groups (P<0.05); for the SAO and CE subtype patients, the levels of blood UA showed no signifi-cant difference between the two groups (P>0.05). Conclusion: In Uygur Nationality and Han Nationality patients with acute cerebral infarction, blood UA level and the various subtypes of TOAST etiology classification show dif-ferent.