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Infection Rate Following Total Joint Arthroplasty in the HIV Population |
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| Authors: | Brian M. Capogna Andrew Lovy Yossef Blum Sun Jin Kim Uriel R. Felsen David S. Geller |
| Affiliation: | 1. Department of Orthopaedic Surgery, New York University Hospital for Joint Diseases, New York, New York;2. Department of Orthopaedic Surgery, Mount Sinai Hospital, New York, New York;3. Department of Orthopaedic Surgery, Albert Einstein College of Medicine, Bronx, New York;4. Division of Infectious Disease and Center for AIDS Research, Montefiore Medical, Center and Albert Einstein College of Medicine, Bronx, New York;5. Department of Pediatrics, Montefiore Medical Center, Albert Einstein College of Medicine, Bronx, New York |
| Abstract: | The purpose of this study is to review a large series of HIV-infected patients who underwent total joint arthroplasty and identify potential risk-factors for infection. Sixty-nine HIV-infected arthroplasty cases were analyzed with 138 matched controls. Deep infection rate following total hip or knee arthroplasty was 4.4% (3 of 69) among HIV cases compared to 0.72% (1 of 138) among controls, yielding a non-significant 6.22 times increased odds of infection (95% CI 0.64–61.0, P = 0.11). Kaplan–Meier survival curves for infection free survival and revision free survival revealed non-significantly decreased survival in HIV cases compared to controls (P = 0.06 and P = 0.09). Our results suggest that the rate of early joint infection following primary total joint arthroplasty in the HIV-infected population is lower than reported in a number of previously published studies. |
| Keywords: | human immunodeficiency virus (HIV) hip knee arthroplasty infection |
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