| 脑胶质瘤辐射敏感性相关基因的研究进展 |
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| 引用本文： | 王洗,刘强. 脑胶质瘤辐射敏感性相关基因的研究进展[J]. 国际放射医学核医学杂志, 2008, 32(5): 311-313 |
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| 作者姓名： | 王洗 刘强 |
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| 作者单位： | 1. 300456 天津, 天津港口医院神经内科;;2. 300192 天津, 中国医学科学院放射医学研究所 |
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| 摘 要： | 脑胶质瘤是中枢神经系统最常见的肿瘤,其生长方式呈浸润性生长,手术中难以切除干净,易发生病灶残留从而引起术后复发,影响患者预后。术后放疗是一项重要的治疗手段,但脑胶质瘤对射线的敏感程度直接影响放疗疗效。综述了脑胶质瘤辐射敏感性相关基因研究的现状和进展。
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| 关 键 词： | 脑胶质瘤 辐射耐受性 基因表达调控 基因 P53 NF-κB |
| 收稿时间： | 2008-05-16 |
The progress of radiosensitive genes of human brain glioma |
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| WANG Xi,LIU Qiang. The progress of radiosensitive genes of human brain glioma[J]. International Journal of Radiation Medicine and Nuclear Medicine, 2008, 32(5): 311-313 |
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| Authors: | WANG Xi LIU Qiang |
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| Affiliation: | 1. Department of Neurology, Tianjin Harbour Pospital, Tianjin 300456, China;;2. Tianjin Key Laboratory of Molecular Nuclear Medicine, Institute of Radiation Medicine, Chinese Academy of Medical Sciences Peking Union Medical College, Tianjin 300192, China |
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| Abstract: | Human gliomas are one of the most aggressive tumors in brain which grow infiltrativly. Surgery is the mainstay of treatment. But as the tumor could not be entirely cut off, it is easy to relapse. Radiotherapy plays an important role for patients with gliomas after surgery. The efficacy of radiotherapy is associated with radio sensitivity of human gliomas. This paper makes a summary of curent situation and progress for radiosensitive genes of human brain gliomas. |
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| Keywords: | Brain glioma Radiosensitivity Gene expression regulation Gene,p53 NF-кB |
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