老年急性脑卒中患者并发低钠血症的机制探讨

目的：探讨老年急性脑卒中患者并发低钠血症的发生率。临床特点及发生机制。方法：回顾分析41例老年急性脑卒中并发低钠血症患者的临床，血清钠及CT资料。结果：老年急性脑卒中并发低钠血症的发生率占同期住院老年脑卒中患者的16．02％，以出血性脑卒中为多见。并发低钠血症者发生昏迷和病死率均高于对照组（均P＜0．05），低钠血症的发生与CT所见的病灶分布密切相关，病灶位于基底节区（含丘脑）及脑室内积血更易发生低钠血症。结论：下丘脑－垂体功能紊乱是引起老年急性脑座中并低钠血症的主要原因之一。

Study on the pathogenesis of hyponatremia following acute stroke in the elderly patients

Objective　To investigate the incidence， clinical characters and pathogenesis of hyponatremia following acute stroke in the elderly patients.Methods　The clinical,serum natrium and CT data of 41 cases with hyponatremia following acute stroke in the elderly patients were retrospectively analysed.Results The incidence of hyponatremia following acute stroke in the elderly patients was 16.02% (taking hemorrhagic stroke),the occurrence of the patients' coma induced by hyponatremia and the fatality rate were higher than the controls (P＜0.05);Hyponatremia correlated closely with the localization of lesions in CT, the focus in brain ganglion (induding thalamus) and hematocele in the ventricles of brain caused easily hyponatremia.Conclusion　Dysfunction of hypothalamus-pituitarium was one of the risk factors in causing hyponatremia following acute stoke in the elderly patients.