参芪地黄汤联合西药治疗IgA肾病疗效观察

目的观察参芪地黄汤联合西药治疗IgA肾病的疗效。方法45例IgA肾病患者随机分为对照组22例和治疗组23例，对照组用常规西医治疗，治疗组在对照组治疗基础上采用辨证服用参芪地黄汤，疗程1个月。观察两组患者的尿常规、24h尿蛋白定量、血肌酐、尿素氮等变化情况。结果治疗组总有效率（91．3％）明显高于对照组（65．2％）（Χ^2=6．02，P〈0．05）；治疗组治疗后24h尿蛋白定量（0．48±0．32）g、尿红细胞计数（25．7±13．6）×10^4／ml明显低于治疗前（1．62±1．05）g、（64．4±30．1）×10^4／ml（t=2．889、2．945，均P〈0．01），与对照组治疗后比较，差异均有统计学意义（均P〈0．01）；两组治疗后血肌酐、尿素氮水平有所下降，但与治疗前比较，差异无统计学意义（t=1．752，P〉0．05）。结论参芪地黄汤联合西药治疗IgA肾病，疗效优于单纯西药治疗。

The curative effects of traditional Chinese medicine plus western medicine on patients with nephropathy (IgAN)

Objective To observe the curative effects of traditional Chinese plus western medicine and west ern medicine on patients with nephropathy(IgAN).Methods 45 cases of IgAN were randondy allocated to two groups.22 cases(control group)were treated with routine western medicine and 23 cages(treatment group)were trea ted based on syndrome differentiation.on a course of treatment.The changes of urine routine;24h urine protein;serum creatinine and BUN were observed in patients with IgAN.Results The total effective rate(91.3%)was significantly higher(65.2%)(x2=6.02,P＜0.05);Treatment after 24h urine protein(0.48±0.32)g,urine BBC count(25.7±13.6)104/ml was significantly lower than before treatment(1.62±1.05)g,(64.4±30.1)104/ml(t=2.889,t=2.945,P＜0.01);two groups after treatment Scr,BUN has dropped,and before treatment had no significant difference (t=1.752,P＞0.05).Conclusion The curative effect of traditional Chinese plus western medicine exerts a better effect than the sole western medicine in patients with IgAN.