Candida endophthalmitis in non-neutropenic critically ill patients |
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| Authors: | J. Nolla-Salas A. Sitges-Serra C. León M. V. de la Torre H. Sancho |
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| Affiliation: | (1) Intensive Care Unit, Hospital Universitari del Mar, P!["compfn"]("/content/t083282782072m43/xlarge8728.gif") Manuel Girona 12,3-1a, 08034 Barcelona, Spain;(2) Department of Surgery, Hospital Universitari del Mar, P Manuel Girona 12,3-1a, 08034 Barcelona, Spain;(3) Intensive Care Unit, Hospital de Valme Sevilla, Spain;(4) Intensive Care Unit, Hospital Virgen de la Victoria Málaga, Spain;(5) Intensive Care Unit, Hospital Reina Sofía Córdoba, Spain |
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| Abstract: | Six non-neutropenic critically ill patients who developed hematogenous endophthalmitis due toCandida spp. were studied prospectively. In all cases the yeast was isolated in blood cultures. The incidence of endophthalmitis in patients with candidemia was 13%, the predominant species beingCandida albicans. Four patients were treated with fluconazole, but its efficacy could not be evaluated because three of the patients died. In patients at risk of candidemia, regular ophthalmoscopic examinations are recommended in order to enable early initiation of systemic antifungal therapy in those who develop endophthalmitis. |
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