| 糖代谢异常对患者冠状动脉内皮功能影响的研究 |
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| 引用本文： | 王琛,王广,何立芸,郝燕婷,洪天配. 糖代谢异常对患者冠状动脉内皮功能影响的研究[J]. 山东医药, 2011, 51(36): 7-8 |
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| 作者姓名： | 王琛 王广 何立芸 郝燕婷 洪天配 |
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| 作者单位： | 北京大学第三医院,北京,100191 |
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| 基金项目： | 国家自然科学基金资助项目(81070701,81070244); 国家重点基础研究发展计划973资助项目(2011CB503904) |
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| 摘 要： | 目的探讨不同病程2型糖尿病患者冠脉血流速度储备（CFVR）功能的变化。方法我院59例门诊就诊患者分为3组：糖耐量正常组23例,新诊断2型糖尿病患者组21例,已诊断2型糖尿病患者组15例。对3组对象应用腺苷诱导的超声心动图检查,探测左前降支血流速度的改变,评估各组间CFVR功能的改变。结果糖耐量正常组、新发糖尿病患者组与已诊断糖尿病患者组CFVR功能逐渐下降,P〈0.01。结论糖尿病患者CFVR功能显著降低,在新诊断的糖尿病患者内皮功能就已受损,而且随着糖尿病病程的延长进一步恶化。
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| 关 键 词： | 糖尿病,非胰岛素依赖型 内皮功能 冠脉血流速度储备 |
Effects of abnormal glucose metabolism on coronary artery endothelial function in patients with type 2 diabetes mellites |
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| WANG Chen,WANG Guang,HE Li-yun,HAO Yan-ting,HONG Tian-pei. Effects of abnormal glucose metabolism on coronary artery endothelial function in patients with type 2 diabetes mellites[J]. Shandong Medical Journal, 2011, 51(36): 7-8 |
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| Authors: | WANG Chen WANG Guang HE Li-yun HAO Yan-ting HONG Tian-pei |
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| Affiliation: | WANG Chen,WANG Guang,HE Li-yun,HAO Yan-ting,HONG Tian-pei (Peking University Third Hospital,Beijing 100191,P.R.China) |
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| Abstract: | Objective To investigate the change of coronary flow velocity reserve(CFVR) in patients with type 2 diabetes mellites for different course.Methods The 59 participants were divided into 3 groups: 23 normal glucose tolerance volunteers(group A),diabetic patients including 21 newly diagnosed(group B) and 15 already diagnosed from outpatient department(group C).The CFVR was assessed by using adenosine echocardiography.Result There was a gradual decline for CFVR among the group A,B and C(P<0.01).Conclusions Coro... |
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| Keywords: | diabetes mellitus non-insulin-dependent endothelial function coronary flow velocity reserve |
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