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心力衰竭并恶液质患者血清脂联素水平与BMI、脑钠肽的关系
引用本文:周南南,卓晶明,东燕,李春梅. 心力衰竭并恶液质患者血清脂联素水平与BMI、脑钠肽的关系[J]. 山东医药, 2011, 51(45): 21-22
作者姓名:周南南  卓晶明  东燕  李春梅
作者单位:山东大学附属省立医院,济南,250021
基金项目:山东省自然科学基金资助项目(Y2006c130)
摘    要:目的探讨心力衰竭(HF)并恶液质患者血清脂联素(ADP)水平与BMI、脑钠肽(BNP)的关系。方法将80例心血管病患者分为三组,A组20例有冠心病(CHD)、HF并恶液质;B组40例有CHD史、HF,无恶液质;C组20例有CHD,无HF。另选14例查体健康者作为对照组。检测各组血清ADP、BNP、左室射血分数,计算其BMI;分析ADP水平与BMI、BNP的相关性。结果 A组血清ADP、BNP明显高于其他三组(P均〈0.01),其ADP水平与BMI呈负相关(r=-0.47,P〈0.01),与BNP呈正相关(r=0.55,P〈0.01)。结论 HF并恶液质患者血清ADP明显升高,提示ADP水平与HF患者发生恶液质有因果关系;ADP水平与BNP呈正相关,提示BNP可能促进血清ADP分泌。

关 键 词:心力衰竭  恶液质  脂联素  脑钠肽  体质量指数

Corelation of serum adiponectin and BMI and BNP in patients with heart failure and cachexia
ZHOU Nan-nan,ZHUO Jing-ming,DONG Yan,LI Chun-mei. Corelation of serum adiponectin and BMI and BNP in patients with heart failure and cachexia[J]. Shandong Medical Journal, 2011, 51(45): 21-22
Authors:ZHOU Nan-nan  ZHUO Jing-ming  DONG Yan  LI Chun-mei
Affiliation:ZHOU Nan-nan,ZHUO Jing-ming,DONG Yan,LI Chun-mei (Provincial Hospital Affiliated to Shandong University,Jinan 250021,P.R.China)
Abstract:Objective To study the association of adiponectin concentration in patients with heart failure(HF) and cachexia with body mass index(BMI) and B-type natriuretic peptide(BNP).Methods A total of 80 patients with coronary artery disease(CHD) were included into 3 groups: group A(HF and cachexia,n=20),group B(HF without cachexia,n=40),group C(no HF,n=20);and a control group of 14 healthy persons were studied as well.BMI were calculated and adiponectin,BNP and LVEF were tested for all subjects.The associations of...
Keywords:hear failure  cachexia  adiponectin  brain natriuretic peptide  body mass index  
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