Neuron-specific enolase expression in a rat model of radiation-induced brain injury following vascular endothelial growth factor-modified neural stem cell transplantation |
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Authors: | Songhua Xiao Chaohui Duan Qingyu Shen Yigang Xing Ying Peng Enxiang Tao Jun Liu |
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Affiliation: | Songhua Xiao~1,Chaohui Duan~2,Qingyu Shen~1,Yigang Xing~1,Ying Peng~1,Enxiang Tao~1,Jun Liu~1 1 Department of Neurology,Second Affiliated Hospital,Sun Yat-sen University,Guangzhou 510120,Guangdong Province,China 2 Department of Laboratory Medicine,China |
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Abstract: | BACKGROUND:Previous studies have shown that transplantation of vascular endothelial growth factor(VEGF)-modified neural stem cells(NSC) provides better outcomes,compared with neural stem cells,in the treatment of brain damage. OBJECTIVE:To compare the effects of VEGF-modified NSC transplantation and NSC transplantation on radiation-induced brain injury,and to determine neuron-specific enolase(NSE) expression in the brain. DESIGN,TIME,AND SETTING:The randomized,controlled study was performed at the Linbaixin... |
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Keywords: | vascular endothelial growth factor neuron-specific enolase neural stem cells radiation-induced brain injury |
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