| 金蛤口服液对急性放射病小鼠免疫功能的影响 |
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| 引用本文： | 蔡乐,李丽,周芳,谭宏宇.金蛤口服液对急性放射病小鼠免疫功能的影响[J].现代中西医结合杂志,2013,22(12):1275-1277. |
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| 作者姓名： | 蔡乐 李丽 周芳 谭宏宇 |
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| 作者单位： | 1. 广西南宁市第二人民医院,广西南宁,530031
2. 广西中医药大学药学院,广西南宁,530001 |
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| 摘 要： | 目的探讨金蛤口服液对放射性小鼠模型免疫功能的影响。方法 60只昆明种小鼠随机分为5组,每组12只,不同剂量金蛤口服液或生理盐水连续灌胃给药6 d。在给药第2天,除对照组外均行X线照射1次,制作免疫功能障碍小鼠模型。检测各组小鼠跳台错误次数和负重游泳时间以及小鼠免疫器官(胸腺、脾脏)质量的变化。结果金蛤口服液可显著降低辐射造成的小鼠错误跳台次数,同时延长辐射造成的负重游泳时间,显著提高放射性小鼠的免疫器官胸腺指数,提高网状内皮系统吞噬功能。结论金蛤口服液对放射性小鼠模型免疫功能有增强作用。
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| 关 键 词： | 急性放射病 免疫功能 金蛤口服液 |
Effect of Golden Clam oral liquid on immunologic function of mice with acute radiation sickness |
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| Cai Le
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Li Li
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Zhou Fang
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Tan Hongyu.Effect of Golden Clam oral liquid on immunologic function of mice with acute radiation sickness[J].Modern Journal of Integrated Chinese Traditional and Western Medicine,2013,22(12):1275-1277. |
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| Authors: | Cai Le Li Li Zhou Fang Tan Hongyu |
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| Abstract: | Objective It is to approach the influence of Golden Clam oral liquid(GCOL) on immunologic function of blood-weak mouse model exposed with X ray.Methods 60 mice were divided into 5 groups,12 cases in each group.All animals were treated by intragastric administration with high,middle and low dose GCOL or physiological saline for 6 days.The mice immune dysfunction model excepted control group were established by exposed with X ray.The changes of weight-carrying swimming time,step-down wrong times and immune organs(thymus,spleen) weight in each group were detected and compared.Results GCOL could markedly improve the blood-weak weight-carrying swimming time,step-down wrong times and mouse thymus index,but also improve the reticuloendothelial system phagocytic function.Conclusion GDOL enhance the immunologic function on blood-weak mouse model exposed with X ray. |
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| Keywords: | acute radiation sickness immunologic function Golden Clam oral liquid |
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