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加减逍遥散治疗肝郁脾虚证慢性乙型肝炎疗效观察
引用本文:孙建光. 加减逍遥散治疗肝郁脾虚证慢性乙型肝炎疗效观察[J]. 中国药物警戒, 2011, 8(5): 269-271
作者姓名:孙建光
作者单位:山东中医药大学附属医院,山东,济南,250011
基金项目:国家重大新药创制技术专项-中药药理学研究与药效评价关键技术(2009ZX09502-015).山东省中医药科技发展计划重点项目-慢性乙型肝炎规范化治疗方案的研究
摘    要:目的 观察加减逍遥散治疗肝郁脾虚证慢性乙型肝炎临床疗效.方法 临床以60例肝郁脾虚证慢性乙型肝炎患者为研究对象,随机分为试验组和对照组各30例.观察患者治疗12周后的临床证候、生化指标、免疫学指标、病原学指标等的改善情况.结果 治疗12周时试验组总有效率83.33%,对照组为66.67%,试验组明显优于对照组(P<0.05).试验组在改善中医证候、生化指标、免疫指标、HBV-DNA转阴率等方面明显优于对照组,二者有统计学差异(P<0.05).结论 逍遥散加减方可有效改善中医证候、调节细胞免疫、恢复肝功能、提高抗病毒的应答率.

关 键 词:加减逍遥散  肝郁脾虚证  慢性乙型肝炎

Effective Observation on Chronic Hepatitis B with Syndrome of Liver Stagnation and Spleen Deficiency Treated by Modified Xiaoyaosan
SUN Jian-guang. Effective Observation on Chronic Hepatitis B with Syndrome of Liver Stagnation and Spleen Deficiency Treated by Modified Xiaoyaosan[J]. Chinese JOurnal of Pharmacovigilance, 2011, 8(5): 269-271
Authors:SUN Jian-guang
Affiliation:SUN Jian-guang(The Affiliated Hospital of Shangdong University of TCM,Shangdong Jinan 250011,China)
Abstract:Objective To observe the clinical effection of modified Xiaoyaosan in treating chronic hepatitis B with Syndrome of liver stagnation and spleen deficiency.Methods 60 patients of chronic hepatitis B with syndrome of liver stagnation and spleen deficiency were chosen for clinical observation,and randomly divided into experimental group and control group.After12 weeks' treatment,to observe the patients' improvements such as clinical symptoms,biochemical indicators,immunological targets,pathogen indicators and ...
Keywords:Modified xiaoyaosan  Syndrome of liver stagnation and spleen deficiency  Chronic Hepatitis B  
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