黛力新联合醒脑静治疗脑卒中后抑郁的临床研究

目的研究黛力新联合醒脑静治疗脑卒中后抑郁的临床疗效。方法选择临床确诊为脑卒中后抑郁患者97例，按就诊先后分成黛力新联合醒脑静治疗为治疗组49例，醒脑静治疗为对照组48例，疗程14d。通过临床神经功能缺损程度（CSS）、汉密尔顿抑郁量表（HAMD）评分以及日常生活能力量表（ADL）评价两组治疗前及治疗14d后疗效。结果治疗组患者临床疗效明显好转，治疗组优于对照组，两组痊愈、显著进步、总有效率比较差异均有统计学意义（P均〈0．05）。两组治疗前HAMD、CSS分值比较，差异无统计学意义（P〉0．05），两组治疗后HAMD评分、CSS评分与同组治疗前比较均有统计学意义（P〈0．05）；与对照组治疗后比较，治疗组变化有统计学意义（P〈0．05）。PSD患者日常生活能力治疗组优于对照组，有显著性差异（P〈0．01）。结论黛力新联合醒脑静治疗可明显改善脑卒中后抑郁患者抑郁症状和神经功能康复，从而提高脑卒中后抑郁患者日常生活能力。

Clinical studies on deanxit combined with xingnaojing in the treatment of post-stroke depression TENG Ruixiang

Objective To study the clinical curative effect of deanxit combined with xingnaojing in the treatment of post-stroke depression. Methods Choose 97 patients with clinical diagnosis of post-stroke depression, according to the clinic were divided into： deanxit combined with xingnaojing therapy for the treatment group （49 cases）, xingnaojing treatment as control group （48 cases）, treated 14 d. Through the clinical nerve function defect degree （CSS）, Hamilton depression scale （HAMD） scores and daily life ability scale （ADL） evaluation of the two groups before treatment and 14 day after treatment efficacy. Results Patient clinical curative effect of treatment group was obviously improved, the treatment group was superior to the control group, two groups of healing, remarkable progress, total efficient compara- tive differences were statistically significant （all P 〈 0.05）. HAMD, CSS Scores between two groups before treatment, there was no statistically significant difference （P 〉 0.05）. two groups of HAMD scores, CSS score after treatment compared with before treatment group had statistical significance （P 〈 0.05）; Changes compared with the control group after treatment, the treatment group was statistically significant （P 〈 0.05 ）. PSD patients daily life ability was better than that of control group, there was significant difference （P 〈 0.01）. Conclusion Deanxit combined with xingnaojing treatment can obviously improve the symptoms of depression in patients with post-stroke depression and neurological functional rehabilitation, thus improve the post-stroke depression patients daily life skills.