管状胃治疗老年食管癌的安全性、有效性观察及其对患者生活质量的影响

目的探讨管状胃治疗老年食管癌的安全性、有效性及其对患者生活质量的影响。方法选择本院收治的老年食管癌患者54例，随机分为研究组和对照组，研究组患者给予管状胃治疗，对照组患者给予全胃代食管治疗，根据食管癌患者生活质量测定量表（QLQ—OES24）测定患者术后1、3、6、12个月的生活质量情况，并统计患者不良反应发生情况。结果两组手术时间、术中出血量、输血量差异无统计学意义：术后随访屁示研究组心律失常、胸部并发症、反流性食管炎、胸胃综合征发生率明显少于对照组（P〈0．05），而两组吻合口瘘、吻合口狭窄发生率无明显差异（P〉0．05）；两组术后1个月生活质量评分差异无统计学意义，术后3、6、12个月，研究组生活质量评分明显高于对照组（P〈0．05）。结论管状胃代食管治疗老年食管癌患者，并发症少，安全性高，患者生活质量改善明显．值得应用。

Safety, efficacy observation of tubular stomach in treatment of elderly patients with esophageal cancer and its impact on the quality of life

Objective To investigate the safety, efficacy of tubular stomach treatment in elderly patients with esophageal cancer and its impact on the quality of life. Methods Fifty-four cases of elderly patients with esophageal cancer admitted to our hospital were randomly divided into study group and the control group,patients in study group were given tubular stomach treatment, the patients of control group were given full stomach replacing esophagus treatment; according to quality of life questionnaire on patients with esophageal cancer（QLQ-OES24 ）, the quality of life of patients in 1 month, 3 months, 6 months, 12 months after treatment were detected, and the adverse events were oh- served. Results The operative time, blood loss, blood transfusion of two groups was not significantly different; Postop- erative follow-up showed arrhythmias, chest complications, reflux esophagitis,thoracic stomach syndrome of study group was significantly less than that of control group（P 〈 0.05 ）, and anastomotic fistula, anastomotic stricture rate of two groups was not significantly different （P 〉 0.05）. Postoperative QLQ score in 1 month had no significantly different, but in 3, 6, and 12 months after surgery, QLQ scores of the study group was significantly higher than that in the control group （P 〈 0.05）. Conclusion The tubular stomach in treatment of elderly patients with esophageal cancer has fewer complications, safety is high, quality of life is improved significantly, it is worth of application.