| 苦豆子栓剂的研制及临床应用 |
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| 引用本文： | 任棣,常威,白进良. 苦豆子栓剂的研制及临床应用[J]. 中国药房, 2002, 13(8): 468-469 |
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| 作者姓名： | 任棣 常威 白进良 |
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| 作者单位： | 兰州医学院附属第一医院,兰州市730000 |
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| 基金项目： | 甘肃省科技厅资助项目 (QS002-C33-010) |
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| 摘 要： | 目的 :研制治疗慢性前列腺炎的栓剂并考察其临床疗效。方法 :以苦豆子总生物碱 (TASa)为主药 ,用酸性染料分光光度法测定TASa的含量 ,并与前列安栓进行对照 ,观察其临床疗效。结果 :TASa的线性范围为0 14～15 4μg/ml,氧化苦参碱对照品的加样回收率为101 2 % ,RSD=0 55 %。结论 :该制剂制备工艺简单 ,质控方法可靠 ;对直肠刺激性小 ,临床疗效确切 ,值得临床推广应用。
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| 关 键 词： | 苦豆子总生物碱 栓剂 质量控制 临床应用 |
| 文章编号： | 1001-0408(2002)08-0468-02 |
| 修稿时间： | 2002-01-18 |
Preparation and Clinical Application of Sophora Alopecurodies Suppository |
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| REN Di,CHANG Wei,BAI Jinliang. Preparation and Clinical Application of Sophora Alopecurodies Suppository[J]. China Pharmacy, 2002, 13(8): 468-469 |
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| Authors: | REN Di CHANG Wei BAI Jinliang |
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| Abstract: | OBJECTIVE:To prepare Sophora alopecurodies suppository for treating prostatitis chronica and observe its clinical therapeutic effect METHODS:The content of the total alkaloid in the suppository was determined with acid dye spectrophotometry and the therapeutic effect was observed in comparison with qianliean suppository RESULTS:The linear range of TASa was 0 14～15 4μg/ml,standard oxymatriner's recovery was 101 2%,RSD=0 55% CONCLUSION:This suppository is simple in preparation,reliable in quality-control It is slight in irritation to rectum and effective in clinical use The preparation is worth popularizing in clinical practice |
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| Keywords: | TASa suppository quality control clinical application |
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