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Transmission of Multidrug-Resistant Salmonella enterica Subspecies enterica 4,[5],12:i:- Sequence Type 34 between Europe and the United States
Authors:Ehud Elnekave  Samuel L. Hong  Seunghyun Lim  Dave Boxrud  Albert Rovira  Alison E. Mather  Andres Perez  Julio Alvarez
Affiliation:Hebrew University of Jerusalem, Jerusalem, Israel (E. Elnekave);University of Minnesota, St. Paul, Minnesota, USA (E. Elnekave, S. Lim, A. Rovira, A. Perez, J. Alvarez);University of Leuven, Leuven, Belgium (S.L. Hong);Minnesota Department of Health, St. Paul (D. Boxrud);Quadram Institute Bioscience, Norwich, UK (A.E. Mather);University of East Anglia, Norwich (A.E. Mather);Universidad Complutense, Madrid, Spain (J. Alvarez)
Abstract:Multidrug-resistant Salmonella enterica subspecies enterica 4,[5],12:i:- sequence type 34 represents a worldwide public health risk. To determine its origin in the United States, we reconstructed a time-scaled phylogeny with a discrete trait geospatial model. The clone in the United States was introduced from Europe on multiple occasions in the early 2000s.
Keywords:Evolution   Salmonella monophasic   Salmonella enterica subspecies enterica   serotype 4  [5]  12:i:-   multidrug-resistance   antimicrobial resistance   foodborne   zoonotic   zoonoses   enteric infections   bacteria   Europe   United States
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