经脾门静脉造影磁共振成像:肝脏灌注均匀度的研究

目的研究经脾门静脉造影磁共振成像(MRSP)在肝脏非病变区的灌注均匀度。方法可疑肝脏占位性病变患者16例,行MRSP检查。扫描分4个时相:平扫期、门静脉期、实质期和延迟期,测量不同时相肝实质和非病变性异常灌注区信号强度。结果MRSP门脉期出现肝脏非病变区的异常灌注率为4/16,共8个灶,均为肝硬化患者,最多见为三角形或扇形(7/8),分布无规律。结论MRSP在门静脉期存在不均匀灌注,但并不影响对病变的诊断;MRSP可得到较均匀的肝脏门脉期强化。

Perfusion homogeneity of hepatic parenchyma in magnetic resonance imaging during splenoportography

Objective To evaluate the homogeneity of hepatic parenchyma enhancement in magnetic resonance imaging during splenoportography (MRSP) in the portal phase. Methods MRSP was performed in 16 patients suspected of space-occupying lesions in the livers. The signal intensity of non-lesion abnormal perfusion areas and that of peripheral parenchyma were measured in all the scanning phases including unenhanced phase, portographic phase, equilibrium phase, and delayed phase. Results Perfusion abnormalities were observed in 8 non-lesion foci in the portal phase in 4 cases of hepatic cirrhosis, most frequently appearing in triangle or fan-like shapes (7/8) with unpredictable locations. Hepatic cirrhosis patients had more non- lesion perfusion abnormalities than non-cirrhosis patients. Conclusions The presence of non-lesion perfusion abnormalities in MRSP does not affect the diagnosis of the disease, and more homogeneous enhancement of the hepatic parenchyma in the portal phase can be achieved in MRSP than in CT during arterial portography and magnetic resonance imaging during arterial portography.