复方甲壳胺消毒剂性能的试验观察

为了解复方甲壳胺消毒剂的杀菌性能和毒性 ,采用定量杀菌试验和动物毒性试验 ,对其杀灭微生物效果、稳定性及毒性进行了试验观察。结果 ,以含 180 0mg/L壳聚糖的消毒液对布片上大肠杆菌、金黄色葡萄球菌作用 3min ,以含 5 4 0 0mg/L的消毒液对白色念珠菌作用 5min ,杀灭率可达 99.90 %以上。有机物对杀菌效果无明显影响。置 5 4℃温箱存放 14d ,其对白色念珠菌的杀灭效果无明显变化。毒理试验表明 ,该消毒剂属实际无毒级 ,对皮肤粘膜无刺激性。结论 ,该消毒剂具较好的杀菌效果 ,性能稳定 ,低毒、无刺激性。

EXPERIMENTAL OBSERVATION ON PROPERTIES OF COMPOUND CHITOSAMINE DISINFECTANT

In order to know the germicidal efficacy and toxicity of compound chitosamine disinfectant, quantitative germicidal test and animal toxicity test were used to observe experimentally its germicidal efficacy, stability and toxicity. The results showed that the killing rates of Escherichia coli and Staphylococcus aureus on cloth strips exposed to the disinfectant solution containing chitosan 1800 mg/L for 3 min and Candida albicans exposed to the disinfectant solution containing chitosan 5400 mg/L for 5 min attained over 99.90%. Organic substance had no significant influence on the germicidal efficacy. Storing in 54℃ incubator for 14 days did not cause obvious change of its efficacy in killing C. albicans. Toxicological test indicated that this disinfectant belongs to actually non-toxic grade and was non-irritative to skin and mucous membrane. Conclusion: This disinfectant has relatively good germicidal efficacy and low toxicity, and is stable and non-irritative.