| 海芒果Cerbera odollam果仁中强心甙的分离鉴定 |
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| 引用本文： | 李荣芷,王云雯,陈毓群.海芒果Cerbera odollam果仁中强心甙的分离鉴定[J].药学学报,1981,16(5):361-365. |
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| 作者姓名： | 李荣芷 王云雯 陈毓群 |
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| 作者单位： | 北京医学院药学系
(李荣芷)，中国科学院上海有机化学研究所
(王云雯)，中国科学院上海有机化学研究所(陈毓群) |
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| 摘 要： | 从海南岛产的海芒果Cerbera odollam果仁中分离到四种强心多糖甙monoacetyl-the-vetinB(Ⅰ)(1) thevetin B(Ⅲ)(2)及它们的7β,8β环氧衍生物tanghinoside(Ⅱ)(3) desacetyl-tanghinoside(Ⅳ)。经果仁中的酶水介获得相应四个单糖甙Cerberin(Ⅴ)(4) neriifolin(Ⅶ)(5) tang hinin(Ⅵ)(6) desacetyl-tanghinin(Ⅷ)(6) tanghinoside,tanghinin及desacetyl-tanghinin以前未从Cerbera odollam中分到过。甙Ⅳ为一新甙。
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| 收稿时间： | 1980-02-12 |
THE SEPARATION AND IDENTIFICATION OF CARDIAC GLYCOSIDES IN THE KERNAL OF CERBERA ODOLLAM |
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| Li Rongzhi,Wang Yunwen,and Chen Yuqun.THE SEPARATION AND IDENTIFICATION OF CARDIAC GLYCOSIDES IN THE KERNAL OF CERBERA ODOLLAM[J].Acta Pharmaceutica Sinica,1981,16(5):361-365. |
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| Authors: | Li Rongzhi Wang Yunwen and Chen Yuqun |
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| Abstract: | Four cardiac glycosides (Ⅰ, Ⅱ, Ⅲ, Ⅳ) were isolated from the kernal of Cerbera odollam growing in Hai-Nan Island. They were identified as monoacetyl-thevetin B (Ⅰ), thevetin B (Ⅲ), and their 7,8,-epoxide derivatives which were tanghinoside (Ⅱ) and desacetyl-tanghinoslde (Ⅳ).By enzymatic hydrolysis with the enzyme existing in the kernal four monoglycosides, cerberin (Ⅴ), neriifolin (Ⅶ), tanghinin (Ⅵ) and desacetyl-tanghinin (Ⅷ) were obtained respectively.Tanghinoside (Ⅱ), tanghinin (Ⅵ) and desacetyl-tanghinin (Ⅷ) had not been isolated from Gerbera odollam previously.Desacetyl-tanghinoside (Ⅳ) was a new compound. |
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