胸腔积液中ADA，LDH和CEA联合检测的诊断价值

目的：研究联合检测胸腔积液中腺苷脱氨酶（ADA）、乳酸脱氢酶（LDH）和癌胚抗原（CEA）对胸腔积液良恶性鉴别的意义。方法：常规采集46例结核性疾病患者和30例恶性疾病患者的胸腔积液,检测ADA、LDH、CEA水平并进行分析。结果：ADA〉40 U/L、CEA〈15μg/L水平作为判断结核性胸腔积液指标的敏感性、特异性、阳性预测值、阴性预测值为85.71%、90.19%、78.94%、90.19%;以ADA〈40 U/L、CEA〉15μg/L水平作为判断恶性胸腔积液指标的敏感性、特异性、阳性预测值、阴性预测值分别为71.74%、85.74%、86.84%、69.77%。结论：联合检测ADA、CEA两项指标有助于鉴别结核性和恶性胸腔积液。

The value of combined detection of ADA, LDH and CEA in the diagnosis of pleural effusion

Objective：To study the significance of the combined detection of pleural effusion ADA,LDH,and CEA on the differential diagnosis of benign and malignant pleural effusion.Methods：Conventional acquisited pleural effusion of 46 cases of patients with tuberculosis and 30 cases of patients with malignant disease,and ADA,LDH,CEA level were detected and analyzed.Results：The sensitivity,specificity,positive predictive value,negative predictive value of ADA〉40 U/L,CEA〈15 μg/L level as indicators to determine tuberculous pleural effusion were 85.71%,90.19%,78.94%,90.19%;the sensitivity,specificity,positive predictive value,negative predictive value of ADA〈40 U/L,CEA〉15 μg/L level as indicators of malignant pleural effusion to determine were 71.74%,85.74%,86.84%,69.77%.Conclusion：Combined detection of ADA,CEA can help differential diagnosis of tuberculosis and malignant pleural effusion.