| 眼眶孤立性神经纤维瘤的临床病理研究 |
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| 引用本文： | 陈娟,魏锐利,徐红霞.眼眶孤立性神经纤维瘤的临床病理研究[J].中国医药导报,2011,8(30):100-102. |
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| 作者姓名： | 陈娟 魏锐利 徐红霞 |
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| 作者单位： | 1. 海军总医院医学整形科,北京,100048
2. 第二军医大学附属长征医院眼科,上海,200003 |
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| 摘 要： | 目的：探讨眼眶孤立性神经纤维瘤的临床及B型超声表现、MRI特点,并结合病理切片讨论MRI信号强弱与组织学的对应关系。方法：对8例患者的临床表现、B型超声、MRI特点及病理结果进行描述。结果：眼眶孤立性神经纤维瘤患者主要临床表现为眼球渐进性突出;B型超声显示眼球后圆形或类圆形,边界清楚,低或中等回声占位性病变,声衰减中等;MRI检查可见眼眶内边界清楚的圆形或类圆形异常信号占位,与玻璃体比较,6例T1加权像（T1WI）呈稍低或中等信号,T2加权像（T2WI）为稍低和较高信号混杂,2例T1WI和T2WI均呈中低信号。8例增强均有轻到中度强化。肿瘤光镜下6例表现为中到大量梭形肿瘤细胞,胞浆嗜酸性,胞核呈梭形,两端较尖,染色深,呈波浪状,细胞呈束状排列,间质含较多胶原纤维和少量黏液样基质。2例肿瘤细胞丰富,生长活跃,呈栅栏状排列,内可见核分裂像,间质含有大量胶原纤维。结论：眼眶孤立性神经纤维瘤其临床表现和影像学检查容易与眼眶内良性肿瘤混淆,确诊必须依靠病理检查。肿瘤的病理构成与MRI信号有一定的关系。
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| 关 键 词： | 眼眶 神经纤维瘤 超声检查 磁共振成像 病理 |
Clinical pathologic study of orbit isolated nerve fibroma |
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| CHEN Juan,WEI Ruili,XU Hongxia.Clinical pathologic study of orbit isolated nerve fibroma[J].China Medical Herald,2011,8(30):100-102. |
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| Authors: | CHEN Juan WEI Ruili XU Hongxia |
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| Institution: | CHEN Juan1,WEI Ruili2,XU Hongxia1 1.Department of Plastic Surgery,Navy General Hospital,Beijing 100048,China,2.Department of Ophthalmology,Changzheng Hospital Affiliated to the Second Military Medical Untiersity,Shanghai 200003 |
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| Abstract: | Objective:To discuss the performance of clinical and type-B ultrasonic,the characteristic of magnetic resonance imaging(MRI) in orbit isolated nerve fibroma and to discuss the correspondence between the signal strength of MRI and histology combined with tissue section.Methods:The performance of clinical and type-B ultrasonic,the characteristic of MRI and the pathological results of 8 cases with orbit isolated nerve fibroma were described.Results:The major clinical manifestation of the patients with orbit is... |
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| Keywords: | Orbit Nerve fibroma Ultrasonography Magnetic resonance imaging Pathology |
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