Acute respiratory infection in a renal transplant recipient. |
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| Authors: | Anna Richards Jenny Ng Kam Chuen Clive Taylor Ralph Jackson Geoffrey Toms David Kavanagh |
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| Institution: | The Freeman Hospital, Newcastle upon Tyne, UK. anna.richards@ncl.ac.uk |
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| Abstract: | |
Introduction
| We report the case of a 43-year-old renal transplant recipientwho required ventilatory support for acute respiratory tractinfection. The differential diagnosis in immunocompromised individualsis extensive and requires prompt investigation.
Case report
| A 43-year-old male non-smoker with end stage kidney failuredue to medullary cystic kidney disease received a 1:1:1 cadavericrenal allograft in 2001. The transplant initially functionedwell, but 1 month after transplantation, his renal functionworsened and a renal transplant biopsy showed mild cellularrejection. He was treated with methylprednisolone (500 mg/dayfor 3 days) and his renal function improved to a baseline creatinineof 160 µmol/l. He subsequently had a cytomegalovirus (CMV)seroconversion illness with diarrhoea and deterioration in renalfunction. This was successfully treated with ganciclovir. For the next 3 years he experienced no medical problems andhis
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| Keywords: | bronchoalveolar lavage human metapneumovirus immunocompromised opportunistic infection renal transplant respiratory tract infection |
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